摘要
目的通过回顾性分析149例中青年非小细胞肺癌(NSCLC)患者的临床资料,了解其临床特点及可能影响预后的因素。方法收集2009年5月—2010年8月在南京医科大学第一附属医院住院并手术病理确诊为NSCLC的149例中青年肺癌患者的临床资料,随访其生存时间,并对相关数据进行分析。结果149例中青年NSCLC患者的平均年龄为(55.2±8.8)岁,男性多见,腺癌为主,Ⅰ、Ⅱ期最多,起病症状以咳嗽、咳痰多见,绝大多数男性有吸烟史,总体1、3、5年生存率分别为96.0%、83.2%和59.7%。结论中青年NSCLC患者以男性居多,腺癌为主,吸烟与肺癌的发生密切相关,病理分期是影响中青年NSCLC患者术后生存时间的因素之一。
ObjectiveThe clinical features of 149 young and middle-aged patients with non-small cell lung cancer(NSCLC)were evaluated to develop better understanding of diagnosis and treatment of NSCLC.MethodsThe clinical data of 149 young and middle-aged patients with NSCLC diagnosed by surgery and pathology who were hospitalized in the First Affiliated Hospital of Nanjing Medical University from May 2009 to August 2010 were collected.Their survival time was followed up and relevant data were analyzed.ResultsThe mean age of 149 NSCLC patients was(55.2±8.8)years and the disease was more common in men.Adenocarcinoma accounted for the highest proportion in all pathological types,most patients were in stageⅠandⅡ.The onset symptoms were mostly cough an1d sputum,most of the males had a history of smoking.The overall 1,3,5-year survival rates were 96.0%,83.2%and 59.7%,respectively.ConclusionsThe majority of young and middle-aged NSCLC patients are male,and the main pathological type was adenocarcinoma.Smoking is closely related to the occurrence of lung cancer,and pathological staging is one of the factors affecting the postoperative survival time of young and middle-aged NSCLC patients.
作者
曲红
金琳羚
何梦钰
解卫平
QU Hong;JIN Linling;HE Mengyu;XIE Weiping(Department of Respiratory and Critical Care Medicine,the First Affiliated Hospital of Nanjing Medical University,Nanjing,Jiangsu 210029,China)
出处
《徐州医科大学学报》
CAS
2020年第1期55-59,共5页
Journal of Xuzhou Medical University
基金
十三五“艾滋病和病毒性肝炎等重大传染病防治”国家科技重大专项(2018ZX10722301-002)
国家自然科学基金(81273571)。
关键词
非小细胞肺癌
中青年
手术
临床特征
吸烟
non-small cell lung cancer
young and middle-aged
surgery
clinical features
smoking
