摘要
目的比较结肠癌在腹腔镜手术与开腹手术中的疗效。方法方便选取2013年2月—2017年3月该院收治的113例结肠癌患者,随机分为腹腔镜组57例和开腹组56例。观察两组手术情况,术后情况及并发症发生情况。结果手术情况:腹腔镜手术组在手术时间、肿瘤大小以及淋巴结清扫数目方面与开腹组差异无统计学意义(P>0.05),但是腹腔镜组术中出血量(85.5±21.1)mL少于开腹组(152.4±33.7)mL,差异有统计学意义(t=17.672,P=0.000)。术后情况:腹腔镜组首次排气时间(2.1±0.5)d、术后住院时间(7.1±2.3)d均少于开腹组首次排气时间(4.3±0.8)d及术后住院时间(10.0±3.1)d,住院费用腹腔镜组(33110.2±3526.7)元高于开腹组(28554.7±2263.5)元,差异有统计学意义(t=17.563,5.654,8.156,P=0.000),腹腔镜组手术后第1天、第3天、第5天的C反应蛋白(CRP)、白细胞(WBC)变化幅度低于开腹组,差异有统计学意义(CRP:t=3.706,8.194,15.530,P=0.000,0.000,0.000,WBC:t=5.297,3.665,2.656,P=0.000,0.000,0.009),显示腹腔镜组术后炎症反应轻。腹腔镜组术后1年、2年生存率、复发率、转移率与开腹组相比差异无统计学意义(P>0.05)。术后并发症情况:手术部分感染、肺部感染、腹腔出血、吻合口瘘二者比较差异无统计学意义(P>0.05)。结论该研究结果表明,腹腔镜手术根治结肠癌相比开腹手术具有创伤小、出血少、住院时间短、胃肠功能恢复快,炎症控制更优等特点,有着广阔前景,值得推广发展。
Objective To compare the efficacy of colon cancer in laparoscopic surgery and open surgery.Methods From February 2013 to March 2017,113 patients with colon cancer admitted to our hospital were convenient randomly divided into 57 patients in the laparoscopic group and 56 patients in the open group.Observed the operation of the two groups,postoperative conditions and complications.Results Surgery situation:there was no statistically significant difference in operative time,tumor size,and lymph node dissection between the laparoscopic group and the open group.However,the amount of bleeding in the laparoscopic group(85.5±21.1)mL was lower than that in the open group(152.4±33.7)mL,the difference was statistically significant(t=17.672,P=0.000).Postoperative condition:the first exhaust time(2.1±0.5)d and postoperative hospital stay(7.1±2.3)din the laparoscopic group were less than the first exhaust time(4.3±0.8)d and postoperative hospital stay(10.0±3.1)d in the open group.The hospitalization cost of laparoscopic group(33110.2±3526.7)yuan was higher than that of open group(28554.7±2263.5)yuan,all of which were statistically different(t=17.563,5.654,8.156,P=0.000),laparoscopy changes of C-reactive protein(CRP)and white blood cells(WBC)on the 1st,3rd,and 5th day after surgery were lower than those in the open group(CRP:t=3.706,8.194,15.530,P=0.000,0.000,0.000,WBC:t=5.297,3.665,2.656,P=0.000,0.000,0.009),indicating that the inflammatory response was light after laparoscopic surgery.There was no significant difference in the 1-,2-year survival rate,recurrence rate,and metastasis rate between the laparoscopic group and the open group.Postoperative complications:there were no significant differences in surgical infection,pulmonary infection,abdominal bleeding,and anastomotic leakage.Conclusion The results of this study show that laparoscopic surgery for colon cancer has the characteristics of less trauma,less bleeding,shorter hospital stay,faster recovery of gastrointestinal function,better inflammation control,and has broad prospects.It is worthy of promotion and development.
作者
林明
LIN Ming(Sanming City Hospital of Integrated Traditional Chinese and Western Medicine,Sanming,Fujian Province,365001 China)
出处
《中外医疗》
2019年第35期52-54,66,共4页
China & Foreign Medical Treatment
关键词
结肠癌
腹腔镜
开腹
疗效
Colon cancer
Laparoscopy
Laparotomy
Curative effect
