摘要
目的探讨靶向药物治疗对晚期肺癌患者生命质量的影响。方法方便选取该院住院部及门诊部在2017年3月—2019年2月期间收治的40例晚期肺癌患者,按摸球法分为对照组(n=20)及观察组(n=20),分别给予常规化疗、吉非替尼治疗;比较两组生活质量、不良反应及总有效率。结果观察组总有效率95.0%高于对照组的65.0%,差异有统计学意义(χ^2=5.625,P=0.018)。观察组生活质量高于对照组,皮疹、骨髓抑制、转氨酶升高、神经毒性及消化系统症状不良反应发生率低于对照组(P<0.05)。结论靶向药物吉非替尼治疗晚期肺癌具显著效果,生活质量改善,值得推广。
Objective To investigate the effect of targeted drug therapy on quality of life in patients with advanced lung cancer.Methods Convenient elect forty patients with advanced lung cancer who were admitted to the inpatient department and outpatient department of the hospital from March 2017 to February 2019 were divided into the control group(n=20)and the observation group(n=20)according to the ball method.Routine chemotherapy and gefitinib were given respectively;the quality of life,adverse reactions and total effective rate were compared between the two groups.Results The total effective rate of the observation group was 95.0%higher than that of the control group(65.0%),the difference was statistically significant(χ^2=5.625,P=0.018).The quality of life of the observation group was higher than that of the control group,and the incidence of rash,bone marrow suppression,elevated transaminases,neurotoxicity and digestive system symptoms was lower than that of the control group(P<0.05).Conclusion The targeted drug gefitinib has significant effects in the treatment of advanced lung cancer,and the quality of life is improved.It is worth promoting.
作者
周梅娟
ZHOU Mei-juan(Department of Oncology,Yixing Cancer Hospital,Yixing,Jiangsu Province,214200 China)
出处
《中外医疗》
2019年第35期16-18,共3页
China & Foreign Medical Treatment
关键词
靶向药物
晚期肺癌
生命质量
不良反应
总有效率
Targeted drugs
Advanced lung cancer
Quality of life
Adverse reactions
Total effective rate
