摘要
目的研究半红树植物玉蕊Barringtoniaracemosa枝叶中的化学成分。方法综合运用硅胶柱色谱、ODS柱色谱和SephadexLH-20凝胶柱色谱以及制备型HPLC等方法进行系统分离和纯化,根据化合物的理化性质和波谱学数据,并通过与文献中报道的数据进行对照鉴定化合物的化学结构。结果从半红树植物玉蕊枝叶的90%乙醇提取物中分离得到了17个化合物,分别鉴定为白杨素(1)、阿亚黄素(2)、芫花素(3)、鼠李柠檬素(4)、小麦黄素(5)、五桠果素(6)、5,3′-二羟基-7,4′-二甲氧基黄酮(7)、5,7,3′,4′-四甲氧基黄酮(8)、5-羟基-6,7,8,3′,4′-五甲氧基黄酮(9)、petasitolone(10)、sarmentol F(11)、dehydrovomifoliol(12)、blumenol A(13)、10-hydroxyaristolan-9-one(14)、麦珠子酸(15)、齐墩果内酯(16)和11,12-去氢熊果酸内酯(17)。结论所有化合物均为首次从玉蕊属植物中分离得到。
Objective To study the chemical constituents of the stems and leaves of semi-mangrove plant,Barringtonia racemosa.Methods The chemical constituents of B.racemosa were separated and purified by silica gel,ODS,Sephadex LH-20 gel column chromatographies and preparative HPLC.Their structures were identified by physicochemical properties,spectroscopic analysis,as well as comparisons with the data reported in literature.Results A total of 17 compounds were isolated from the 90%ethanol extract of the stems and leaves of B.racemosa,which were identified as chrysin(1),ayanin(2),genkwanin(3),rhamnocitrin(4),tricin(5),dillenetin(6),5,3'-dihydroxy-7,4'-dimethoxyflavone(7),5,7,3',4'-tetramethoxyflavone(8),5-hydroxy-6,7,8,3',4'-pentamethoxy flavone(9),petasitolone(10),sarmentol F(11),dehydrovomifoliol(12),blumenol A(13),10-hydroxyaristolan-9-one(14),alphitolic acid(15),oleanolic lactone(16),and 11,12-dehydroursolic acid lactone(17).Conclusion All compounds are isolated from the genus Barringtonia for the first time.
作者
郭嘉铭
于绡梅
苏芹婷
张威
戴莹莹
刘艳萍
付艳辉
GUO Jia-ming;YU Xiao-mei;SU Qin-ting;ZHANG Wei;DAI Ying-ying;LIU Yan-ping(Engineering Research Center for Industrialization of Southern Medicinal Plants Resources of Hainan Province,Hainan Normal University,Haikou 571158,China;Key Laboratory of Tropical Medicinal Resource Chemistry of Ministry of Education,Hainan Normal University,Haikou 571158,China)
出处
《中草药》
CAS
CSCD
北大核心
2019年第23期5690-5695,共6页
Chinese Traditional and Herbal Drugs
基金
国家自然科学基金资助项目（21967008）
国家自然科学基金资助项目（21662011）
国家自然科学基金资助项目（31660097）
海南省重点研发计划项目（ZDYF2019049）
海口市重点研发计划项目（2017050）
教育部创新团队项目（IRT-16R19）
关键词
半红树植物
玉蕊
黄酮
倍半萜
三萜
白杨素
芫花素
小麦黄素
5
7
3′
4′-四甲氧基黄酮
麦珠子酸
semi-mangrove
Barringtonia racemosa(L.)Spreng
flavonoids
sesquiterpenes
triterpenoids
chrysin
genkwanin
tricin
5,7,3'4'-tetramethoxyflavone
alphitolic acid
