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利妥昔单抗对非霍奇金淋巴瘤化疗患者肿瘤标志物及免疫功能的影响 被引量:5

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摘要 非霍奇金淋巴瘤(NHL)为一组异质性极强的独立疾病,在常见的恶性肿瘤排名中居前十位[1]。NHL通常病变于脾脏、淋巴结与胸腺等器官,且除淋巴结之外的淋巴组织与器官也可能发生。患者通常表现出皮肤病变、盗汗、发热与盗汗等症状,病情严重时,甚至可能会发生全身功能障碍[2]。对于本病的治疗,临床上可通过局部放疗、生物免疫学及手术切除等手段进行,CHOP方案(环磷酰胺+多柔比星+长春新碱+泼尼松)为目前临床上常用的化疗方案,但临床实践发现其疗效不甚理想,且容易引起不良反应,长时间用药易形成耐药性[3]。伴随临床研究的深入,发现将利妥昔单抗与化疗联合运用可增强疗效。本研究对NHL化疗患者提供利妥昔单抗治疗,探析其对患者肿瘤标志物与免疫功能的影响。具体内容如下。
出处 《中国药物与临床》 CAS 2020年第1期82-84,共3页 Chinese Remedies & Clinics
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