摘要
目的:探讨家庭规模与已婚女性复发性抑郁障碍患者临床特征及共病的关系。方法:将4328名已婚女性复发抑郁障碍患者依据家庭规模分为无子女组(452例)、独生子女组(2460例)和多子女组(1416例),比较各组间临床特征及共病情况。结果:临床表现:与其他两组比较,无子女组首发年龄及最严重发作时年龄小,不典型症状多,生物学症状数少,死亡想法及自杀行为多;自杀相关问题较独生子女组多;坐立不安、无价值感和症状总数较多子女组少。与多子女组比较,独生子女组首发年龄小,发作次数少,无价值感、自卑感、死亡及自杀意念少(P<0.05或P<0.01)。共病情况:和多子女组比较,无子女组和独生子女组共病忧郁症相对少见,无子女组共病社交恐怖症相对多见,独生子女组共病情境恐怖症、血液恐怖症相对多见;和独生子女组比较,无子女组血液恐怖症相对较少(P<0.05或P<0.01)。结论:女性复发性抑郁障碍患者中,无子女患者不典型症状及自杀相关问题较突出;多子女患者无价值感、自卑明显,生物学症状、症状总数及共病忧郁更多。
Objective:To investigate the relationship between family size and clinical characteristics and comorbidity in married female patients with recurrent depressive disorder(RDD). Method:Total 4 328 married female RDD patients were divided into childless group(452 cases),only child group(2 460 cases) and multi-child group(1 416 cases) according to their family sizes.Clinical features and comorbidity among the 3 groups were compared. Results:Clinical features:Compared with the other two groups,the childless group had relatively younger age of first onset and the worst period, more atypical symptoms,fewer biological symptoms, more death thoughts and suicide behavior.Furthermore,there were more death thoughts and suicide related problems in the childless group than those in the only child group, and restlessness,worthlessness and number of symptoms were less than those in the multi-child group.Compared with the multi-child group,the age of first onset in the only child group was younger,number of attacks was less,worthlessness,inferiority,ideations of death and suicide were less(P<0.05 or P<0.01).Comorbidity:Compared with the multi-child group,the ratios of comorbid melancholia in the childless group and only child group were relatively lower,the ratio of comorbid social phobia in the childless group was relatively higher,the ratios of comorbid situational phobia and blood phobia in the only child group were relatively higher.Compared with the only child group,the ratio of comorbid blood phobia in the childless group was relatively lower(P<0.05 or P<0.01). Conclusion:Among the female RDD patients,atypical symptoms and suicide related problems are more prominent in childless patients. The multi-child patients have more obvious worthlessness and low self-esteem, more symptoms and higher ratio of comorbid melancholia.
作者
魏燕
汪周兵
张震
张广华
WEI Yan;WANG Zhou-bing;ZHANG Zhen;ZHANG Guang-hua(Zhenjiang Mental Health Center,Zhenjiang 212003,China)
出处
《临床精神医学杂志》
2019年第6期389-392,共4页
Journal of Clinical Psychiatry
基金
英国惠尔康基金(H5ROON0)
镇江市科技支撑-发展项目(SH2014095)
镇江市卫生科技重点专项(SHW2015012)
关键词
女性复发性抑郁障碍
家庭规模
临床特征
共病
female recurrent depressive disorder
family size
clinical characteristics
comorbidity
