摘要
目的:探讨肾移植术后并发卡氏肺孢子虫肺炎(PCP)的早期诊断和治疗。方法:综合分析我院2018年3月〜2019年3月间肾移植术后并发P C P者4例。其发病时间均在术后3〜6个月内,初始症状均为发热、伴有呼吸闲难和干咳。用深部诱导痰法检测病原体,口服联黄屮氧苄啶片治疗,疗程大于2周,并辅以对症支持治疗。结果:4例患者痰液分析均检测出卡氏肺孢子虫,经治疗临床症状消失,胸部C T等检查恢复正常。所有患者随访3〜5个月,无卡氏肺孢子虫肺炎复发结论:对于肾移植术后早期(3〜6个月),出现发热、呼吸困难、干咳等临床表现者,应高度怀疑PCP,深部诱导痰检测法是早期诊断PCP的有效手段,尽早治疗是PCP治愈的关键。
Objective:To investigate the early diagnosis and treatment of Pneumocystis carinii pneumonia(PCP)after renal transplantation.Methods:From March 2018 to March 2019 in our hospital,there were 4 patients with PCP after renal transplantation,including 3 males and 1 female.The onset time was 3 to 6 months after surgery,the initial symptoms were fever,accompanied by difficulty breathing and dry cough.The pathogens detected by deep induced sputum were treated with conjugated trimethoprim tablets for more than 2 weeks,supplemented by symptomatic supportive treatment.Results:The sputum analysis of these 4 patients showed the presence of Pneumocystis carinii.After treatment,the clinical symptoms disappeared and chest CT examination returned to normal.During 3 to 5 months of follow-up,no recurrence of Pneumocystis carinii pneumonia was found in all the patients.Conclusion:For patients with early clinical manifestations(3 to 6 months),such as fever,dyspnea,dry cough,etc.PCP should be highly suspected.Deep induced sputum can he the effetive choice for early diagnosis of PCP.Early treatment is the key to the success of PCP cure.
作者
刘海龙
邓益森
应文伟
李沛哲
何宇辉
丁振山
周晓峰
LIU Hai-long;DENG Yi-sen;YING Wen-wei(Journal of China-Japan Friendship Hospital)
出处
《中日友好医院学报》
2019年第6期335-337,388,F0002,共5页
Journal of China-Japan Friendship Hospital
关键词
卡氏肺孢子虫肺炎
肾移植
i秀导痰
诊断
治疗
Pneumocystis carinii pneumonia
kidney transplantation
induced sputum
diagnosis
therapy
