摘要
目的观察中医辨证辅助治疗经皮冠状动脉介入(PCI)术后心绞痛的临床疗效。方法62例PCI术后心绞痛患者随机分为治疗组和对照组各31例。对照组给予常规治疗,治疗组在对照组基础上给予中医辨证治疗,均治疗4周。比较两组患者中医证候疗效、心绞痛疗效、心电图疗效;比较两组患者治疗前后硝酸甘油使用量、血脂[甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C),总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)]、超敏C反应蛋白(hs-CRP)及D-二聚体水平。结果两组患者中医证候疗效(治疗组总有效率为87.10%,对照组为58.06%)、心绞痛疗效(治疗组总有效率为80.65%,对照组为70.97%)、心电图疗效(治疗组总有效率为77.42%,对照组为67.74%)比较,治疗组均优于对照组(P<0.05)。治疗后两组患者硝酸甘油用量、TC、TG、LDL-C、D-二聚体、hs-CRP均较治疗前明显下降(P<0.05),且治疗后治疗组低于对照组(P<0.05);两组治疗后HDL-C均较治疗前明显升高(P<0.05),且治疗组高于对照组(P<0.05)。结论中医辨证辅助治疗可显著改善PCI术后心绞痛患者中医证候、缓解心绞痛,并改善血脂水平、降低hs-CRP以及D-二聚体水平、减少硝酸甘油用量。
Objective To investigate the clinical effect of traditional Chinese medicine(TCM)syndrome differentiation in the treatment of angina pectoris after percutaneous coronary intervention(PCI).Methods A total of 62 patients with angina pectoris after PCI were randomly divided into a treatment group(31 cases)and a control group(31 cases).The control group was given conventional treatment,and the treatment group was given corresponding TCM syndrome differentiation treatment on the basis of the control group.Both groups were treated for 4 weeks.The efficacy of TCM syndrome,angina pectoris and electrocardiogram were compared between the 2 groups.The nitroglycerin use,blood lipids[triglyceride(TG),high density lipoprotein cholesterol(HDL-C),total cholesterol(TC),low density lipoprotein cholesterin(LDL-C)],high-sensitivity C-reactive protein(hs-CRP)and D-dimer(DD)levels were compared before and after treatment.Results In comparison of the efficacy of TCM symptom(87.10%in the treatment group and 58.06%in the control group),angina pectoris(80.65%in the treatment group and 70.97%in the control group)and electrocardiogram(77.42%in the treatment group and 67.74%in the control group),the treatment group was all superior to the control group(P<0.05).After treatment,nitroglycerin usage,TC,TG,LDL-C,DD and hs-CRP of the 2 groups were significantly decreased than before(P<0.05),and the level of above indexes of the treatment group was lower than those of the control group(P<0.05).After treatment,HDL-C of the 2 groups was significantly increased than before(P<0.05),and the level of HDL-C of the treatment group was higher than that of the control group(P<0.05).Conclusion TCM syndrome differentiation treatment can significantly improve TCM symptoms,relieve angina pectoris,improve blood lipid levels,reduce hs-CRP and DD levels,and reduce the amount of nitroglycerin in patients with angina pectoris after PCI.
作者
黄传惠
樊瑞红
刘洪斌
HUANG Chuanhui;FAN Ruihong;LIU Hongbin(Affiliated Hospital of Tianjin Academy of Traditional Chinese Medicine,Tianjin,300120;Tianta Street Community Health Service Center in Hexi District,Tianjin)
出处
《中医杂志》
CSCD
北大核心
2019年第24期2118-2122,共5页
Journal of Traditional Chinese Medicine
关键词
经皮冠状动脉介入治疗
中医辨证
心绞痛
血脂
超敏C反应蛋白
D-二聚体
percutaneous coronary intervention
traditional Chinese medicine syndrome differentiation
angina pectoris
blood lipid
high-sensitivity C-reactive protein
D-dimer
