摘要
目的分析食管癌术后康复期患者症状特征及影响因素,为制定针对性的症状干预策略提供参考。方法选取2018年3~10月我院行食管癌手术治疗的216例患者为调查对象,其中男180例、女36例,年龄(63.7±8.3)岁。在患者术后1个月采用自行设计症状调查表进行症状调查与评估。结果术后1个月发生率排前5位的症状依次为反流(48.6%)、咳嗽(42.6%)、吞咽困难(40.7%)、声音嘶哑(12.0%)、腹泻(11.6%)。女性患者更容易发生反流(OR=2.053)、乏力(OR=1.932)、胸痛(OR=3.681)、失眠(OR=2.419)、腹痛(OR=3.882)、恶心(OR=3.014)及呕吐(OR=2.505)症状,年龄≥60岁的患者更容易发生吞咽困难(OR=2.274),食管胸下段癌比食管胃结合部癌患者更容易发生吞咽困难(OR=0.326),术前行新辅助化疗更容易发生反流(OR=1.594),开放手术(OR=3.681)、术前行新辅助放疗(OR=2.495)的患者是发生胸痛的影响因素。结论食管癌术后康复期患者存在多种症状,且症状的发生率与患者性别、年龄、肿瘤部位、手术方式和新辅助放化疗密切相关。
Objective To analyze the symptom characteristics and influencing factors in order to provide reference for symptom management of patients with esophageal cancer after operation.Methods A total of 216 esophageal cancer patients,including 180 males and 36 females with an average age of 63.7±8.3 years,who underwent surgical operation in our hospital from March to October 2018 were recruited and investigated with self-designed symptom questionnaire at 1 month after surgery.Results The top five symptoms were acid reflux(48.6%),cough(42.6%),dysphagia(40.7%),hoarseness(12.0%),and diarrhea(11.6%).Women were more prone to acid reflux(OR=2.053),fatigue(OR=1.932),chest pain(OR=3.681),sleep disturbance(OR=2.419),abdominal pain(OR=3.882),nausea(OR=3.014)and vomiting(OR=2.505).Patients over 60 years were more prone to dysphagia(OR=2.274).Patients with lower thoracic esophageal cancer had a higher incidence of dysphagia compared with patients with carcinoma of esophagogastric junction(OR=0.326).Patients who had neoadjuvant chemotherapy were more likely to suffer acid reflux(OR=1.594).Open surgery(OR=3.681)and neoadjuvant radiotherapy(OR=2.495)were the risk factors of chest pain.Conclusion There are many symptoms in patients with esophageal cancer after operation,and the occurrence of symptoms is closely related to gender,age,tumor location,surgical procedure and neoadjuvant chemoradiotherapy.
作者
缪艳
谢钦
李亚玲
罗春艳
冷雪峰
韩泳涛
MIAO Yan;XIE Qin;LI Yaling;LUO Chunyan;LENG Xuefeng;HAN Yongtao(Department of Thoracic Surgery,Sichuan Cancer Hospital&Research Institute,Sichuan Cancer Center,School of Medicine,University of Electronic Science and Technology of China,Chengdu,610041,P.R.China)
出处
《中国胸心血管外科临床杂志》
CAS
CSCD
2020年第1期52-56,共5页
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
关键词
食管癌
外科手术
康复期
症状
Esophageal cancer
surgery
rehabilitation
symptoms
