摘要
慢性假性肠梗阻(CIPO)是一种罕见但严重的肠道运动障碍性疾病,其特征是在无机械性肠梗阻情况下肠运动功能受到损害。CIPO可能由于原发性和继发性因素损害肠神经系统(神经病变),平滑肌(肌病)和(或)Cajal间质细胞(间质病)所致。CIPO易漏诊和误诊,治疗极其困难,主要基于营养支持、药物和外科治疗。目前肠道微生态在CIPO中的发生、发展及治疗中的作用日益受到关注,可能成为CIPO新的治疗方法。
Chronic intestinal pseudo-obstruction(CIPO)is a rare but serious intestinal dyskinesia characterized by impaired bowel motor function in the absence of mechanical intestinal obstruction. CIPO may be caused by primary and secondary factors that damage the enteric nervous system(neuropathy),smooth muscle(myopathy),and/or Cajal interstitial cells(interstitial disease). CIPO is extremely easy to missed diagnosis and misdiagnosis.The treatment of CIPO is very difficult.It is based on nutritional support,medicine and surgical treatment.At present,the occurrence,development and treatment of intestinal micro-ecology in CIPO has gradually attracted attention and may become a new treatment method for CIPO.
作者
陈启仪
姜军
CHEN Qi-yi;JIANG Jun(Shanghai Tenth People’s Hospital,Tenth People’s Hospital of TongJi University,Shanghai 200072,China)
出处
《中国实用外科杂志》
CSCD
北大核心
2019年第12期1291-1295,共5页
Chinese Journal of Practical Surgery
基金
国家自然科学基金面上项目(No.81670493)
关键词
慢性假性肠梗阻
肠平滑肌
肠神经系统
CAJAL间质细胞
小肠细菌过度繁殖
chronic intestinal pseudo-obstruction
intestinal smooth muscle
enteric nervous system
Cajal interstitial cells
small intestine bacterial overgrowth
