摘要
Microtubules are dynamic cytoskeletal structures essential for shaping cellular architecture and driving cell motility.Their tube-like structure typically comprises 13 protofilaments,each of which is formed of a/p tubulin heterodimers arranged in a head-to-tail manner(Howard,2001).The formation of microtubules primarily contains two processes.The first process in which soluble dimers start to form a growing microtubule is termed microtubule nucleation(Figure 1A).