摘要
目的:分析血浆1,3-β-D葡聚糖在新生儿真菌性败血症诊断及疗效评估中的应用。方法:2017年8月-2018年12月收治新生儿真菌性败血症患儿43例纳入观察组,另取同期分娩健康新生儿43例纳入对照组。开展血常规检查、真菌血培养检查、血浆1,3-β-D葡聚糖含量检测,比较两组检测结果。结果:观察组血小板低于对照组,血浆1,3-β-D葡聚糖高于对照组,差异均有统计学意义(P<0.05)。43份患儿标本共分离出19株念珠菌,以光滑念珠菌最为常见。观察组治疗后血浆1,3-β-D葡聚糖水平低于治疗前,差异有统计学意义(P<0.05)。结论:血浆1,3-β-D葡聚糖用于新生儿真菌性败血症检查,可为早期诊断及疗效评估提供支持。
Objective:To analyze the application of plasma 1,3-β-D-glucan in the diagnosis and efficacy evaluation of neonatal fungal septicemia.Methods:43 cases of neonatal fungal septicemia were selected as the observation group from August 2017 to December 2018.In addition,43 healthy newborns in the same period were included in the control group.The blood routine test,fungal blood culture test and plasma 1,3-β-D-glucan content test were carried out,and the results of the two groups were compared.Results:The platelet in the observation group was lower than that in the control group,and the plasma 1,3-β-D-glucan was higher than that in the control group,the differences were statistically significant(P<0.05).A total of 19 candida strains were isolated from 43 children's specimens,of which candida glabrata was the most common.The plasma level of 1,3-β-D-glucan in the observation group after treatment was lower than that before treatment,the difference was statistically significant(P<0.05).Conclusion:Plasma 1,3-β-D-glucan can be used in the detection of neonatal fungal septicemia,which can provide support for early diagnosis and efficacy evaluation.
作者
李芬
谭潭
徐玉娟
侯权芳
黄玲
Li Fen;Tan Tan;Xu Yujuan;Hou Quanfang;Huang Ling(Chenzhou First People's Hospital Affiliated to Nanhua University,Hunan Chenzhou 423000)
出处
《中国社区医师》
2019年第36期142-142,144,共2页
Chinese Community Doctors
