摘要
目的观察柴枣汤加减治疗痰热内扰型失眠的疗效。方法将200例痰热内扰型失眠患者随机分为治疗组和对照组各100例。治疗组给予柴枣汤加减治疗,每日1剂,对照组给予艾司唑仑片,每次1 mg,睡前服,两组疗程均为4周。观察两组患者治疗前后失眠严重程度指数量表(ISI)、匹兹堡睡眠质量指数(PSQI)、睡眠状况自评量表(SRSS)评分变化,并评价临床疗效。结果治疗组患者治愈62例,显效24例,有效10例,无效4例,总有效率为86%;对照组患者治愈50例,显效10例,有效38例,无效2例,总有效率为60%。治疗组总有效率明显高于对照组(P<0.01)。两组患者治疗后的ISI、PSQI、SRSS评分均较治疗前明显下降(P<0.05)。治疗组患者治疗后的ISI、PSQI、SRSS评分均明显低于对照组(P<0.05)。结论柴枣汤加减可以有效提高痰热内扰型失眠患者睡眠质量。
Objective To observe the curative effects of Chaizao Decoction(柴枣汤)on insomnia caused by phlegm heat and internal disturbance.Methods A total of 200 insomnia patients were randomly divided into a treatment group and a control group,with 100 patients in each group.The treatment group was treated with Chaizao Decoction,one dose per day.The control group was treated with esazolam,1 mg each time,taking before sleep.The course of treatment was 4 weeks.The changes of Insomnia Severity Index(ISI)scores,Pittsburgh Sleep Quality Index(PSQI)scores,Self-Rating Scale of Sleep(SRSS)score before and after treatment were observed.Results In the treatment group,62 cases were cured,24 cases significantly effective,10 cases effective,4 cases ineffective,with the total effective rate 86%;in the control group,50 cases were cured,10 case significantly effective,38 cases effective,2 cases ineffective,with the total effective rate 60%.The total effective rate of the treatment group was significantly better than that of the control group(P<0.01).ISI,PSQI and SRSS scores of patients in both groups were significantly decreased after treatment.ISI,PSQI and SRSS scores of patients in the treatment group were significantly lower than those in the control group after treatment(P<0.05).Conclusion Modified Chaizao Decoction could effectively improve the sleep quality of insomnia patients caused by phlegm heat and internal disturbance.
作者
秦保锋
徐燕
严骅
QIN Baofeng;XU Yan;YAN Hua(Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai,201203)
出处
《中医杂志》
CSCD
北大核心
2019年第22期1942-1945,共4页
Journal of Traditional Chinese Medicine
基金
国家中医药管理局第六批全国老中医药专家学术经验继承项目
关键词
失眠
柴枣汤
痰热内扰
匹兹堡睡眠质量指数
失眠严重程度指数量表
insomnia
Chaizao Decoction(柴枣汤)
internal disturbance of phlegm heat
Pittsburgh Sleep Quality Index(PSQI)
Insomnia Severity Index(ISI)
