摘要
目的:探究慢性肾病蛋白尿患者接受黄芪益母汤治疗的临床效果。方法:以慢性肾病蛋白尿患者50例作为此研究对象,所选时间为2016年6月-2018年6月,以简单随机化法分组实验组(25例)和对照组(25例),两组均接受基础治疗,对照组在基础治疗上接受培哚普利治疗,实验组则在基础治疗上接受黄芪益母汤治疗,分析两组慢性肾病蛋白尿患者患者治疗的效果、治疗前后肾功能指标的差异。结果:实验组慢性肾病蛋白尿患者治疗的总有效率(96.00%)明显较对照组总有效率(76.00%)高(P <0.05);两组治疗后的血肌酐(Creatinine,Cr)、尿素氮(Blood Urea Nitrogen,BUN)、尿白蛋白的排泄率(Urinary Albumin Excretion,UAE)水平均较治疗前降低,血浆蛋白水平较治疗前升高,其中实验组治疗后的血浆蛋白水平明显高于对照组,其UAE水平低于对照组,差异有统计学意义(P <0.05);两组慢性肾病蛋白尿患者治疗后的中医证候积分均较治疗前降低,其中实验组治疗后的中医证候积分明显低于对照组,差异存在统计学意义(P <0.05);两组患者不良反应发生率相比,差异无统计学意义(P> 0.05)。结论:慢性肾病蛋白尿患者接受黄芪益母汤治疗能够较好改善肾内血流动力学,控制蛋白尿的排泄量,控制疾病进展速度,提高治疗效果,改善预后情况。
Objective: To explore the clinical efficacy of the Huangqi Yimu decoction( 黄芪益母汤) on chronic nephritic proteinuria. Methods: 50 patients were divided into the experimental group(25 cases) and the control group(25 cases). The control group received basic treatment plus perindopril, and the experimental group received the Huangqi Yimu decoction more. Results: The total efficiency was 96.00% in the experimental group, more than 76.00% in the control group(P<0.05). The serum creatinine, BUN and UAE were lower than those before treatment, and plasma protein was higher than before treatment. Plasma protein in the experimental group was significantly higher than the control group, and UAE was lower(P<0.05). The TCM syndrome scores were lower than those before treatment, and those in the experimental group were lower(P<0.05). There was no significant difference in adverse reactions between two groups(P>0.05). Conclusion: The Huangqi Yimu decoction can improve renal hemodynamics, control proteinurial excretion, improve prognosis.
出处
《中医临床研究》
2019年第31期97-100,共4页
Clinical Journal Of Chinese Medicine
关键词
黄芪益母汤
慢性肾病蛋白尿
治疗效果
The Huangqi Yimu decoction
Chronic nephritic proteinuria
Efficacy
