摘要
目的:观察艾灸联合抗敏解痉汤对小儿咳嗽变异性哮喘免疫球蛋白及T淋巴细胞亚群的影响。方法:选取2016年3月至2018年5月在本院治疗的小儿咳嗽变异性哮喘90例作为研究对象,按照随机数字表法分为对照组和观察组,各45例。对照组给予孟鲁司特钠咀嚼片治疗,观察组给予艾灸联合抗敏解痉汤治疗,观察两组临床疗效及对患儿免疫球蛋白、T淋巴细胞亚群的影响。结果:观察组治疗后IgA、IgG水平均高于对照组,差异有统计学意义(P<0.05);观察组治疗后IgE水平低于对照组,差异有统计学意义(P<0.05);观察组治疗后CD3^+、CD4^+及CD4^+/CD8^+水平均高于对照组,差异有统计学意义(P<0.05);观察组治疗后CD8^+水平低于对照组,差异有统计学意义(P<0.05);两组治疗后恶心呕吐、腹泻、肝肾功能异常发生率差异无统计学意义(P>0.05);观察组治疗后1个月、3个月及6个月复发率均低于对照组,差异有统计学意义(P<0.05)。结论:艾灸联合抗敏解痉汤治疗小儿咳嗽变异性哮喘能提高患儿免疫球蛋白、T淋巴细胞亚群水平,降低复发率,且治疗安全性较高。
Objective:To observe the influence of moxibustion in combination with Anti-Allergic and Spasmolytic Decoction on immunoglobulin and T lymphocyte subsets of cough variant asthma in children.Methods:Ninety cases of cough variant asthma in children treated in our hospital from March 2016 to May 2018 were selected as the research objects,and divided into the control group and the observation group according to random number table method,with 45 cases in each group.The control group was treated with Montelukast Sodium Chewable Tablets,while the observation group was treated with moxibustion combined with Anti-Allergic and Spasmolytic Decoction The clinical efficacies of two groups and the influence on immunoglobulin and T lymphocyte subsets of cough variant asthma in children were observed.Results:The levels of IgA and IgG in the observation group were higher than those in the control group after the treatment and all the differences were statistically significant(P<0.05).The level of IgE in the observation group was lower than that in the control group after the treatment and the difference was statistically significant(P<0.05).The levels of CD3^+,CD4^+,and CD4^+/CD8^+ in the observation group were higher than those in the control group after the treatment and all the differences were statistically significant(P<0.05).The level of CD8+in the observation group was lower than that in the control group after the treatment and the difference was statistically significant(P<0.05).The incidence of nausea,vomiting,diarrhea and abnormal liver and kidney function after the treatment in the two groups had no significant difference after the treatment(P>0.05).The recurrence rate in the observation group was lower than that in the control group at 1,3 and 6 months respectively after the treatment(P<0.05).Conclusion:Moxibustion in combination with Anti-Allergic and Spasmolytic Decoction has a remarkable efficacy on cough variant asthma in children,can improve the level of immunoglobulin and T lymphocyte subsets,reduce the recurrence rate,and has high treatment safety.
作者
熊芳
XIONG Fang(Dangyang People's Hospital,Dangyang,Hubei,China,444100)
出处
《河南中医》
2019年第11期1763-1766,共4页
Henan Traditional Chinese Medicine
关键词
小儿咳嗽变异性哮喘
艾灸疗法
抗敏解痉汤
免疫球蛋白
T淋巴细胞亚群
cough variant asthma in children
moxibustion therapy
Anti-Allergic and Spasmolytic Decoction
immunoglobulin
T lymphocyte subsets
