摘要
目的探讨PCT(降钙素原)、SAA(血清淀粉样蛋白A)、SOD(超氧化物歧化酶)、IL-10(白介素-10)检测对脓毒血症的应用探讨。方法选取2017年1月~2018年1月我院收治的脓毒血症患者52例作为研究组,再选取52例健康人群作为对照组,分别对两组研究对象进行PCT、SAA、SOD、IL-10检测,对比两组研究对象的检测水平,以及PCT与各炎症因子的相关性分析。结果研究组患者的PCT、SAA、IL-10检测水平均显著高于对照组,SOD水平低于对照组(P<0.05);PCT与SAA成正相关,PCT与ESA、Neu无相关性,PCT与WBC的相关性较弱(P<0.05)。结论PCT、SAA、SOD、IL-10均可诊断脓毒血症,四种方法联合检测具有较好的诊断价值,值得在临床广泛推广应用。
Objective To explore the application of PCT(procalcitonin),SAA(serum amyloid A),SOD(superoxide dismutase)and IL-10(interleukin-10)detections in sepsis.Methods 52 patients with sepsis who were admitted and treated in our hospital from January 2017 to January 2018 were selected as the study group.52 healthy people were selected as the control group.PCT,SAA,SOD and IL-10 detections were given to research objects in two groups.The detection levels of research objects in two groups were compared and the correlation between PCT and various inflammatory factors were compared.Results The PCT,SAA and IL-10 detection levels in the study group were significantly higher than those in the control group,and SOD level was lower than that in the control group(P<0.05).PCT was positively correlated with SAA,while PCT had no correlation with ESA and Neu while PCT was weakly correlated with WBC(P<0.05).Conclusion PCT,SAA,SOD and IL-10 all can diagnose sepsis.The combined detection of the four methods has a good diagnostic value and is worthy of widespread promotion and application in clinical practice.
作者
陈婉婵
刘见欢
黄金时
林春明
梁逸仙
CHEN Wanchan;LIU Jianhuan;HUANG Jinshi;LIN Chunming;LIANG Yixian(Department of Laboratory,the Third People’s Hospital of Dongguan,Guangdong,Dongguan 523326,China)
出处
《中国医药科学》
2019年第19期135-137,共3页
China Medicine And Pharmacy
基金
广东省东莞市社会科技发展（一般）项目（2018507150241501）
