摘要
目的 探讨脑卒中后抑郁症的临床特征 ,并对相关因素进行分析 .方法 采用汉密尔顿 (HAMD)抑郁量表对 97例卒中后抑郁症和 78例内源性抑郁症的评分进行分析 ;使用CT或 (和 ) MRI确定病灶部位 ,并结合 HAMD抑郁量表的分值对病灶部位与抑郁的发生进行研究 .结果 抑郁症发生率为 33% .抑郁的发生与患者性别、病变性质无显著性差异(P>0 .0 5 ) .颅脑 CT或 (和 ) MRI示左侧半球比右侧半球、前半球比后半球更易发生抑郁 ,抑郁程度左侧重于右侧 ,前部重于后部 .卒中后抑郁症的焦虑 /躯体化症状发生高于内源性抑郁症 ,而认知障碍尤其是绝望感低于内源性抑郁症 .卒中后抑郁症的严重程度以轻中度者居多 (89.7% ) .结论 卒中后抑郁症的临床表现有一定特点 ,在治疗卒中同时应早发现并及时治疗 。
AIM To study the clinical properties of post stroke depression and carry out an analysis of its related factors. METHODS 97 cases of post stroke depression and 78 cases of endogenous depression were retrospectively analysized using Hamilton depression scale (HAMD) assessment. Pathologic sites were located with CT and/or MRI. The relationship between pathologic sites and occurance of depression was analysized using values of HAMD scale. RESULTS The frequency of depression was 33%. The frequency was notrelated signicicantly to patients' sex and pathologic properties ( P <0.05). Cerebral CT and/or MRI showed that left hemisphere and anterior part of the brain was easier to appear depression than right hemisphere and posterior part of the brain; the degree of depression in left hemisphere and anterior part was more severe than that in right hemisphere and posterior part. The frequency of anxiety/physical symptoms in post stroke depression was higher than that in endogenous depression. However, the frequency of perceptive disorder and despair in post stroke depression was lower than that in endogenous depression. Finally, the majority of the post stroke depression cases (89.7%) were of mild or middle degree. CONCLUSION Post stroke depression has specific clinical properties. In the course of stroke treatment, post stroke depression should be found early and treated early so as to achieve better curative effect.
出处
《第四军医大学学报》
北大核心
2002年第19期1817-1819,共3页
Journal of the Fourth Military Medical University
关键词
脑卒中
抑郁症
对照临床试验
stroke
depression
controlled clinical trials
