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辛伐他汀及阿司匹林对冠心病患者C反应蛋白的影响 被引量:3

The effects of simvastatin and aspirin on C-reactive protein in patients with coronary artery disease
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摘要 目的:探讨辛伐他汀及阿司匹林对冠心病患者反应蛋白的影响。C方法:观察例冠心病患者的反应蛋白在用药89C前后的变化。其中辛伐他汀组例,阿司匹林组例,辛伐他汀和阿司匹林联用组例。272933结果:三组患者用药前后反应蛋C白的改变均有显著性差异(P<而辛伐他汀及阿司匹林联用组用药后反应蛋白的浓度与另两组用药后反应蛋白的浓度0.05),CC比较亦有显著性差异(P<)。0. Objective: To study the effects of simvastatin and aspirin on C-reactive protein in patients with coronary artery disease. Methods: The changes of CRP concentrations before and after the treatment in 89 patients with coronary artery disease were investigated. Among these patients, 27 were in simvastatin group, 29 in aspirin group and 33 in simvastatin and aspirin group. Results: The CRP concentrations in the three groups after the treatment were significantly lower than those before the treatment. In addition, the CRP in simvastatin and aspirin group were significantly lower than those in the other two groups after the treatment (P<0.01). Conclusion: The reduction effects of simvastatin and aspirin on CRP concentrations were superior to those of single simvastatin or aspirin.
出处 《重庆医科大学学报》 CAS CSCD 2002年第3期329-330,共2页 Journal of Chongqing Medical University
关键词 C反应蛋白 冠心病 辛伐他汀 阿司匹林 C-reactive protein Coronary artery disease Simvastatin Aspirin
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  • 2[2]Paul M Ridker, Mary Cushman, Meir J, et al. Inflammation,Aspirin, and the risk of cardiovascular disease in apparently healthy men[J].N Engl J Med, 1997;336:973-979.
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