摘要
目的 :探讨冠状动脉 (冠脉 )内支架置入术后再狭窄与血清尿酸的关系。方法 :2 13例冠脉内支架术后患者因胸痛复发或医生动员行冠脉造影随访 ,以支架置入段内径狭窄≥ 5 0 %为再狭窄。记录这些患者的冠心病易患因素 ,并测定血清尿酸浓度。结果 :2 13例患者共 2 5 7处病变所置入的支架中 ,支架内再狭窄 87例 (138处病变 ) ,其血清尿酸浓度明显高于无再狭窄患者 (P <0 .0 5 )。多因素Logistic逐步回归分析显示 :高尿酸血症是支架内再狭窄的独立危险因素 (OR =1.15 )。结论 :高尿酸血症与冠脉内支架再狭窄明显相关 。
Objective:To assess the relationship between serum concentration of uric acid and intracoronary in stent restenosis. Methods: Follow up of coronary angiography was performed in 213 patients due to recurrence of chest pain or doctor's advise. In stent restenosis was defined as luminal diameter narrowing of intracoronary stent by 50% or greater. Risk factors for coronary artery disease were recorded and serum concentration of uric acid was measured. Results: In 213 patients, 257 coronary stents were implanted. In stent restenosis was occurred in 138 lesions of 87 patients. Serum concentration of uric acid in in stent restenosis group was much higher than that in non in stent restenosis group (P< 0.05 ). Multivariate logistic regression analysis revealed that hyperuricemia was an independent risk factor of in stent restenosis (OR= 1.15 ).Conclusion: There is a close relationship between serum uric acid and in stent restenosis. The occurrence of in stent restenosis may be reduced by lowering serum concentration of uric acid.
出处
《临床心血管病杂志》
CAS
CSCD
北大核心
2002年第8期359-360,共2页
Journal of Clinical Cardiology
