摘要
目的 :探讨幽门螺杆菌 (HP)感染与冠心病的关系。方法 :通过检测血清中抗 HPIgG抗体、C反应蛋白 (CRP)和高密度脂蛋白 (HDL) ,研究HP感染对血清中CRP和HDL调节在冠心病发生中的作用。结果 :冠心病病人的HP感染率明显高于对照组 (P<0 0 5 )。在抗 HPIgG阳性的冠心病病人中CRP明显高于抗 HPIgG阴性组 (P <0 0 1) ,而HDL则相反 (P <0 0 1)。结论 :幽门螺杆菌感染导致CRP升高和HDL降低与冠心病发生密切相关。
Objective: Our purpose was to study relationship between helicobacter pylori (HP) infection and coronary heart diseases.Methods: We detected the serum anti HP antibody IgG, C reactive protein (CRP), and high density lipoprotein (HDL) to investigate the effects of HP regulated serum CRP and HDL on the development of coronary heart diseases.Results: The rate of helicobacter pylori infection in patients with coronary heart diseases was higher than that of the control (P<0 05). The concentration of serum CRP in the anti HP IgG positive cases was higher than that in the anti HP IgG negative ones (P<0 01), but the concentration of serum HDL was lower (P<0 01).Conclusion: The increase of serum CRP and the decrease of serum HDL induced by helicobacter pylori infection was closely associated with the coronary heart diseases.
出处
《中国医科大学学报》
CAS
CSCD
北大核心
2002年第5期371-372,共2页
Journal of China Medical University
关键词
冠心病
幽门螺杆菌感染
关系
coronary heart disease
helicobacter pylori
