摘要
目的 利用心肌肌钙蛋白I(cTnI)反应心肌细胞分子水平变化 ,对中老年患者上腹部及胸腔手术的麻醉方法进行比较。方法 随机选择 6 0例中老年上腹部及胸腔手术患者分为 3组 :胸段硬膜外阻滞组 (TEA组 ) ,全身麻醉组 (GA组 ) ,胸段硬膜外复合全身麻醉组 (CGEA组 ) ,选取麻醉前、麻醉开始后 3小时两点采血检测cTnI ,记录血压、心率变化。结果 GA组血清cTnI麻醉前后比较差异有显著意义 (P <0 .0 1) ,TEA与CGEA组差异无显著意义 (P >0 .0 5 )。结论 TEA和CGEA对中老年手术患者cTnI血清浓度无明显影响 ;
Objective\ The conditions of myocardium cells are correlated with cTnI,through which we compare anesthesia methods used to epigastrium and thoratic cavity of older patients.Methods\ 60 patiens (ages ranging from 45 to 75) were randomly allocated to 3 groups:group TEA(thoracic epidural anesthesia n=20),group GA(general anesthesia ,n=20) and group CGEA (general anesthesia combined with TEA, n=20). The blood samples were taken from peripheral vein before anesthesia and 3 hours after anesthesia to examine cTnI and HR and MAP were also recorded. Results\ cTnI level in group GA was obviously higher (P<0.01),but there were no significant differences in cTnI in group TEA and group CGEA. Conclusion\ TEA and CGEA have no significant effect on cTnI of the older patients undergoing operation and both are superior to GA for older patients.
出处
《皖南医学院学报》
CAS
2002年第4期296-298,共3页
Journal of Wannan Medical College
基金
院中青年科研基金 (编号YK2 0 0 0 13 )资助
关键词
静脉内麻醉
全身麻醉
硬膜外麻醉
吸入麻醉
肌钙蛋白I
手术时间
anesthesia,intravenous
anesthesia,general
anesthesia,inhalation
anesthesia,epidural
troponin I
intraoperative period
