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III IV期原发肝癌的治疗探讨

AN INVESTIGATION ON THE TREATMENT OF PRIMARY CANCER OF THE LIVER WITH STAGE Ⅲ AND Ⅳ
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摘要 目的 报告 6 1例ⅢⅣ期肝癌的生存率 ,其中 5 3例采用不同方法治疗 ,探讨合理的治疗方法。 方法  17例单纯肝动脉导管化疗栓塞 (HAE) ;17例单纯放疗 (RT)和 6例低剂量放疗(LDRT) ;12例HAE +RT ;8例未做特殊治疗 (NT) ;1例单独免疫治疗 (BRM )。结果 6 1例的 1、2、3年绝对生存率是 4 7 5 %、2 4 6 %、8 6 % ,治疗 4 7例的 1、2、3年生存率是 6 1 7%、31 9%、11 4 % ,HAE +RT组 ;RT组 ;HAE组 ;NT和LDRT组的 1、2、3年生存率分别是 83 3%、5 8 3%、2 7 3% ;6 4 7%、35 3%、6 7% ;4 1 2 %、5 9%、0 ;HAE +RT组 ,HAE组与HAE之间生存率对比有明显差异 (P <0 0 5 )。 结论 HAE +RT组疗效好于HAE组 ,HAE组与RT组的接近 ,各治疗组结果均优于LDRT和NT组。笔者提出对晚期肝癌仍要采取积极治疗 ,但要根据肝功能和全身情况给予合理和适量的治疗 ,主张合理程序的综合治疗措施联合采用 :HAE、RT、BRM。 Objective Report survival rates of 61 patients with primary cancer of the liver on stage Ⅲ and IV, of the results of 53 patients were treated with different kinds of therapy. Methods 17 patients were treated by the HAE alone; 17 patients received radiation therapy alone and 6 received a non-effective radiation therapy ( the dose 10~20 GY); 12 were treated by the HAE + RT; 8 did not receive specific treatment for tumor; 1 patient was treated by BRM Results The 1~? 2~? 3~? year survival rates of 61 patients were 47 5%?24 6%? 8 6% respectively, of 47 treated patients were 61 7%, 31 9%,11 4% respectively The 1~, 2~, 3~ year survival rates of HAE +RT group, RT group, HAE group, NT and LDRT groups were 83 3%? 58 3%? 27 3%; 64 7%? 35 3%? 6 7%; 41 2%? 5 9%? 0 respectively; 0 There was a significant difference between the two groups of HAE+RT and HAE in survival rates ( P < 0 05 ) Conclusions The survival results of group HAE+RT were better than that of group HAE and same as group RT To give an active treatment for liver carcinoma with stage Ⅲ Ⅵ, it is to propose by penman, in light of the circumstances of hepatic function, assert overall treated method of reasonably proceeding of combining suchas : HAE,RT,BRM
出处 《青海医学院学报》 CAS 2002年第3期22-25,共4页 Journal of Qinghai Medical College
关键词 原发肝癌 治疗 肝动脉导管化疗栓塞 放射疗法 primary cancer of the liver HAE RT
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