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晚期大肠癌化学治疗进展 被引量：12

Progress of chemotherapy in advanced colorectal cancer
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摘要 全身化疗能控制晚期大肠癌症状 ,延长生存时间 ,提高生活质量。 5 氟尿嘧啶 ( 5 FU )仍是大肠癌治疗的基本药物 ,其生化调节化疗方案优于单纯 5 FU治疗 ,含有依林特肯或草酸铂的 5 FU联合化疗已成为晚期大肠癌新的标准治疗方案 ;口服希罗达已证实至少能取得与静脉注射 5 FU相同的疗效 ,但最佳化疗方案、给药方式仍有争论。
作者 林英城 林雯 林懿
机构地区 汕头大学医学院附属肿瘤医院内科
出处 《国外医学（肿瘤学分册）》 CAS 2002年第5期393-396,共4页 Foreign Medical Sciences (Cancer Section)
关键词 晚期大肠癌 药物疗法 联合化疗
分类号 R735.34 [医药卫生—肿瘤] R730 [医药卫生—肿瘤]
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参考文献27

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  • 2Wils J,Sahmoud T,Sobrero A,et al.Evaluation of clinical efficacy of new medical treatments in advanced colorectal cancer.Results of workshop organized by the EORTC GITCCG[J].Tumori,1998,84(3):335-347.
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  • 5Ragnhammar P,Hafstmm L,Nygren P,et al.A systematic overview of chemotherapy effects in colorectal cancer[J].Acta Oncol,2001,40(2-3):282-308.
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  • 7Thirion P,Piedhois P,Buyse M,et al.Alpha interferon does not increase the efficacy of 5-fluorouracil in advanced colorectal cancer[J].Br J Cancer,2001,84(5):611-620.
  • 8Sobrero A,Guglielmi A,Cirillo M,et al.5-fluorouracil modulated by leucovorin,methotrexate and mitomycin:highly effective,lowcost chemotherapy for advanced colorectal cancer[J].Br J Cancer,2001,84(8):1023-1028.
  • 9Schmoll HJ,Kohne CH,Lorenz M,et al.Weekly 24h infusion of high-dose(HD)5-fluorouracil(5-FU24h)with or without folinic acid (FA vs.bolus 5-FU/FA(NCCTG/Mayo)in advanced colorectal cancer(CRC):A randomized phase Ⅲ study of the EORTC GITCCG and the AIO[J].Proc Am Soc Clin Oncol,2000,19:241a.
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同被引文献35

  • 1黄培钰,张力,洪明晃.鼻咽癌的化疗现状[J].实用肿瘤杂志,2004,19(4):277-281. 被引量：8
  • 2胥彬 刘健 等.羟基喜树碱的药理研究与临床应用[J].中国肿瘤临床,2000,:3-9.
  • 3Seymoar MT, Stemming SP, Cassidy J. Altitudes and practice in the management of metastatic colorectal cancer in Britain Colorectal cancer working party of the UK Medical Research Council [J]. Clin Oncol, 1997, 9 (4): 248-251.
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  • 5de Gramont A, Figer A, Seymour M, et al. Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer[J] .J Clin Oncol,2000,18(16) :2938-2947.
  • 6Saltz LB, Cox JV, Blank C, et al. Irinotecan plus fluorouracil and leucovorin for metastatic colorectal cancer[J]. N Engl J Med,2000,343(13): 905-914.
  • 7Rothenberg ML, Meropol NJ, Poplin EA, et al. Mortality associatedwith irinotecan plus bolus fluorouracil/leucovorin: summary findings of an independent panel[J] .J Clin Oncol,2001,19(18) :3801-3807.
  • 8罗荣城 韩焕兴.肿瘤综合诊疗新进展[M].北京:人民军医出版社,2003..
  • 9Seymour MT,Stenning SP,Cassidy J. Attitudes and pratice in the management of metastatic colorectal cancer in Britain .Colorectal cancer working party of the UK medical research council [J]. Clin Oncol, 1997,9(4):248-251.
  • 10Knight RD, Miller LL, Pirotta N, et al. First-line irinotecan CPT-11 Fluorouracil (F) leucovorin (L) especially improves survival(OS) in metastatic colorectal cancer (MCRC) patients (PT) with favorable prognostic indicators [J]. Proc Am Soc Clin Oncol, 2000,19:255.

引证文献12

二级引证文献22

国外医学（肿瘤学分册）
2002年 第5期

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