摘要
目的 :探讨1H MRS在脑梗死患者脑内代谢物浓度差别及应用于脑梗死患者的优化序列参数。方法 :对 2 4例脑梗死患者脑内代谢物不同1H MRS序列进行对比研究。采用SPSS 10 .0统计分析软件 ,分组研究各主要代谢物的信噪比、半高宽、相对浓度的差别。结果 :脑梗死病灶与健侧之间NAA/Cho、Cho/Cr、Glx/Cr、Lac/Cr差异均有显著性意义 (P<0 .0 5 ) ;其中NAA/Cho、Lac/Cr差异有极显著意义 (P <0 .0 1)。LacSNR 2 5与 13 6、2 5与 2 72之间差异有显著性意义 (P<0 .0 5 )。结论 :1H MRS可以较好地显示脑梗死病灶病理生理变化 ,短回波显示乳酸率高 ,但准确性低。长回波可将Lac与脂质分开。TE =13 6、2
Objective:To study the value of 1HMRS in brain infarction.Methods: 1HMRS was performed in 24 patients.The influence of different sequences on SNR?width at 50% and ratios of metabolites were investigated.Results:There was significant difference between the group of normal and infarction in NAA/Cho?Cho/Cr?Glx/Cr?Lac/Cr,the significances were less than 0.05.Conclusion:Long echo is better in viewing Lac than short echo.
出处
《放射学实践》
2002年第6期461-463,共3页
Radiologic Practice