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人类免疫缺陷病毒夫妻传播的调查 被引量:24

Survey on HIV Transmission Between Married Spouses
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摘要 目的 了解夫妻间HIV传播情况。方法 对某艾滋病高发农村有偿供浆员及其配偶作询问调查并采静脉血作HIV检测 ,对其中一方为供浆员且HIV阳性 ,配偶为非供浆员的 5 4对夫妻作分析研究。结果  5 4对夫妻中 6对发生HIV传播 ,传播率为 11 1% (6 / 5 4 )。HIV由丈夫传给妻子占 8 3% (2 / 2 4 ) ,妻子传给丈夫占 13 3% (4/ 30 ) ,无明显差异 ,P >0 0 5。艾滋病 (AIDS)和艾滋病相关综合征 (ARC)病人HIV传播率 (2 3 8% )显著高于HIV携带者(3 0 % ) ,P <0 0 5。结论 在艾滋病高发地区 ,夫妻间HIV传播是造成AIDS进一步蔓延的重要原因之一。但HIV婚内性传播率比较有多个性伴侣者低 。 Objective To estimate the HIV transmission between married spouses.Methods Former paid plasma donors and their married spouses selected from a highly epidemic area of AIDS were interviewed and blood samples were taken for anti HIV tests.Results Fifty four former paid plasma donors who were positive for anti HIV and their married spouses who had no history of blood donation were studied.Six married couples among the 54 spouses were anti HIV positive.The HIV transmission rate was 11 1%(6/54) during a period of more than 4 year.The transmission rate from husband to wife(8 3%)was not significantly different from that of wife to husband(13 3%), P >0 05.The HIV transmission rate of patient with AIDS (23 8%) was significantly greater than that of HIV-carrier(3 0%), P <0 05.Conclusion HIV transmission between spouses led to further transmission of AIDS in area where plasma donation was the major mode of HIV transmission.However the HIV transmission rate between married couples was relative low compared to persons who had multiple sexual partners,which suggested that the HIV transmission through daily contact within family was not common.
出处 《中国公共卫生》 CAS CSCD 北大核心 2002年第11期1359-1360,共2页 Chinese Journal of Public Health
关键词 人类免疫缺陷病毒 夫妻间传播 艾滋病 HIV感染 HIV transmission between spouses AIDS
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  • 1中华人民共和国国家标准:HIV/AIDS诊断标准及处理原(GB16000-1995).艾滋病的诊断与治疗[M].第1版.北京:人民军医出版社,2000.
  • 2Ahmad K. Higher concentrations of HIV-1 in serum aids viral transmission, lancet 2000, 355 (9211): 1246.
  • 3Hira S.K.,J Kamanga, R Macuacua, et al. Genital ulcers and male circumcision as risk factors for acquiring HIV-1in Zambia. J Inf Dis, 1990, 161:584-585.
  • 4Cohen MS. Sexually transmitted diseases enhance HIV transmission:no longer a hypothesis. Lancet 1998;351 supp(3) :5-7.
  • 5Cohen MS, Hoffman IF, Royce RA, et al. Reduction of concentration of HIV- 1 in semen after treatment of urethritis: implications for prevention of sexual transmission of HIV- 1.

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