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新生儿败血症病原菌及其药敏分析 被引量:1

Analysis of pathogen and drug sensitivity in neonatal septicemia
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摘要 目的  了解新生儿败血症病原菌及药物敏感情况 ,以减少临床上应用抗生素的盲目性 ,降低耐药菌的产生。 方法 对 2 0 0 1年 1— 12月收住我院新生儿科临床诊断败血症的 72例患儿进行细菌培养。用法国生物梅里埃微生物鉴定及药物敏感分析仪 ,做细菌鉴定及药敏试验。 结果  共培养出细菌 73株 ,凝固酶阴性葡萄球菌 (3 0株 )及金黄色葡萄球菌 (2 5株 ) ,为主要致病菌。 结论  几乎全部细菌对青霉素耐药 ,对红霉素及苯唑西林耐药率均超过 75 % ,对万古霉素及环丙沙星高度敏感。几株革兰阴性杆菌对庆大霉素。 Objective To explore the pathogen and drug sensitivity in neonatal septicemia,reduce the undisciplined usage of antibiotics in clinics and decrease the proliferation of drug resisted pathogen.Methods Blood samples were cultured in 72 cases of neonatal septicemia from January to December in 2001.The pathogen and drug sensitivity were identified using Bio Merieux VITEK 32 and Bact/Alert 120 analysor (France).Results Seventy three strains of bacteria were cultured.Coagulase negative staphylococcus(30 strains) and staphylococcus aureus(25 strains) are the main pathogens.Conclusion Nearly all bacteria are resistant to benzylpenicillin,more than 75% are resistant to erythromycin and oxacillin.They are sensitive to vancomycin and ciprofloxacin.A few gram negative bacilli are sensitive to gentamicin,amikacin and the third generation cephaloporin.
出处 《小儿急救医学》 2002年第4期206-208,共3页 Pediatric Emergency Medicine
关键词 新生儿败血症 病原菌 药敏试验 抗生素 合理用药 neonate septicemia pathogen drug sensitivity
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参考文献3

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二级参考文献1

  • 1T. A. Wichelhaus,J. Schulze,K. P. Hunfeld,V. Sch?fer,V. Brade. Clonal heterogeneity, distribution, and pathogenicity of methicillin-resistantStaphylococcus aureus[J] 1997,European Journal of Clinical Microbiology & Infectious Diseases(12):893~897

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  • 1Stoll B J,Hansen N,Fanaroff AA,et al.Late-onset sepsis in very low birth weight neonates:The experience of the NICHD neonatal research network.pediatrics,2002,110:285-291.
  • 2Hyde TB,Hilger TM,Reingold A,et al.Trends in incidence and antimicrobial resistance of early-onset sepsis:Population-based surveillance in San Francisco and Atlanta.Pediatrics,2002,110 (4):690-695.
  • 3宋韶鸣.新生儿败血症[J].新生儿科杂志,2001,16(5):233-234. 被引量:49
  • 4黄丽秀,陈玉蓉,钟斌,魏钰书.新生儿败血症病原学及药敏结果分析[J].四川医学,2003,24(1):82-83. 被引量:5
  • 5中华医学会儿科学分会新生儿学组,余加林,吴仕孝.新生儿败血症诊疗方案[J].中华儿科杂志,2003,41(12):897-899. 被引量:1043

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