摘要
目的 了解新生儿败血症病原菌及药物敏感情况 ,以减少临床上应用抗生素的盲目性 ,降低耐药菌的产生。 方法 对 2 0 0 1年 1— 12月收住我院新生儿科临床诊断败血症的 72例患儿进行细菌培养。用法国生物梅里埃微生物鉴定及药物敏感分析仪 ,做细菌鉴定及药敏试验。 结果 共培养出细菌 73株 ,凝固酶阴性葡萄球菌 (3 0株 )及金黄色葡萄球菌 (2 5株 ) ,为主要致病菌。 结论 几乎全部细菌对青霉素耐药 ,对红霉素及苯唑西林耐药率均超过 75 % ,对万古霉素及环丙沙星高度敏感。几株革兰阴性杆菌对庆大霉素。
Objective To explore the pathogen and drug sensitivity in neonatal septicemia,reduce the undisciplined usage of antibiotics in clinics and decrease the proliferation of drug resisted pathogen.Methods Blood samples were cultured in 72 cases of neonatal septicemia from January to December in 2001.The pathogen and drug sensitivity were identified using Bio Merieux VITEK 32 and Bact/Alert 120 analysor (France).Results Seventy three strains of bacteria were cultured.Coagulase negative staphylococcus(30 strains) and staphylococcus aureus(25 strains) are the main pathogens.Conclusion Nearly all bacteria are resistant to benzylpenicillin,more than 75% are resistant to erythromycin and oxacillin.They are sensitive to vancomycin and ciprofloxacin.A few gram negative bacilli are sensitive to gentamicin,amikacin and the third generation cephaloporin.
出处
《小儿急救医学》
2002年第4期206-208,共3页
Pediatric Emergency Medicine