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异环磷酰胺与MESNA的药理学及临床毒理学 被引量：16

PHARMACOLOGY. CLINICAL TOXICOLOGY AND DOSE SCHEDULE OF IFOSFAMIED/MESNA
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摘要 本文简要叙述了异环磷酰胺与环磷酰胺的结构差别,代谢途径、中枢神经系统毒性及肾毒性的发生机制及影响因素。并列有较详尽的参考文献供查考。 Strucfcral difference of IFO to CTX, main route of metabolism and mechanism of renal and central nervous system toxicity were described.
作者 W.P.Brade K.Herdrich U.Kochel-Fischer C.E.Araujo 管忠震
机构地区 德国法兰克福ASTA药厂国际医学部肿瘤科
出处 《癌症》 SCIE CAS CSCD 北大核心 1992年第3期171-173,共3页 Chinese Journal of Cancer
关键词 异环磷酰胺 MESNA 药理学 毒理学
分类号 R979.1 [医药卫生—药品]
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参考文献12

  • 1Anthony D. Elias,Lois J. Ayash,J. Paul Eder,Cathy Wheeler,Joan Deary,Lisa Weissman,Myla Hunt,John Critchlow,Lowell Schnipper,Emil Frei,Karen H. Antman. Escalating doses of carboplatin with high-dose ifosfamide using autologous bone marrow as support: a phase I study[J] 1991,Journal of Cancer Research and Clinical Oncology(4):S208～S213
  • 2Gregory P. Sutton,John A. Blessing,Guy Photopulos,Michael L. Berman,Howard D. Homesley. Early phase II Gynecologic Oncology Group experience with ifosfamide/mesna in gynecologic malignancies[J] 1990,Cancer Chemotherapy and Pharmacology(1):S55～S58
  • 3Stella M. Davies,Andrew D. J. Pearson,Alan W. Craft. Toxicity of high-dose ifosfamide in children[J] 1989,Cancer Chemotherapy and Pharmacology(1):S8～S10
  • 4Pax H. B. Willemse,Paul E. Jong,Job B. Elema,Nanno H. Mulder. Severe renal failure following high-dose ifosfamide and mesna[J] 1989,Cancer Chemotherapy and Pharmacology(5):329～330
  • 5C. Focan,J. Boossy,D. Focan-Henrard,M. Reginster,J. J. Claessens. Phase II trial with high-dose ifosfamide and mesna given in a 24-h infusion for advanced GI tract cancer[J] 1989,Cancer Chemotherapy and Pharmacology(3):192～193
  • 6Martin Moncrieff,Anabell Foot. Fanconi syndrome after ifosfamide[J] 1989,Cancer Chemotherapy and Pharmacology(2):121～122
  • 7J. Smeitink,M. Verreussel,C. Schr?der,R. Lippens. Nephrotoxicity associated with ifosfamide[J] 1988,European Journal of Pediatrics(2):164～166
  • 8Maria A. Gieron,Larry S. Barak,Jaime Estrada. Severe encephalopathy associated with ifosfamide administration in two children with metastatic tumors[J] 1988,Journal of Neuro - Oncology(1):29～30
  • 9T. Cerny,J. M. Margison,N. Thatcher,P. M. Wilkinson. Bioavailability of ifosfamide in patients with bronchial carcinoma[J] 1986,Cancer Chemotherapy and Pharmacology(3):261～264
  • 10N. Brock,J. Pohl. Experimental basis of modern ifosfamide therapy[J] 1986,Journal of Cancer Research and Clinical Oncology(1):S28

同被引文献45

引证文献16

二级引证文献35

癌症
1992年 第3期

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