摘要
背景与目的:广州市是我国工业城市之一,调查不同工业行业职业人群恶性肿瘤死亡情况,对识别恶性肿瘤高危人群和进一步探讨职业因素与恶性肿瘤关系具有重要意义。本研究旨在通过追踪广州市不同工业行业8年恶性肿瘤的死亡情况,为有针对性做好肿瘤防治提供资料。方法:以1989～1992年399家企业的个人健康档案为资料,严格按流行病学和统计学的调查统计监测,分别追踪观察35岁以上79573名工人8年余,统计其总死亡率、恶性肿瘤死亡率。结果:经过8年余的追踪观察,共追踪633869人年(男393373,女240496),总死亡人数1577人,恶性肿瘤为主死因801人,占50.7%。在各行业中,冶金行业恶性肿瘤的死亡率,明显高于其他行业,橡胶行业职工老年前期组的恶性肿瘤死亡率相对危险较中年组升高。在恶性肿瘤死亡分类中,消化系统、呼吸系统、鼻咽部肿瘤,分别占死亡率前三位,而单一脏器肿瘤死亡率前三位分别为肺癌、肝癌和鼻咽癌顺序排列。结论:恶性肿瘤目前仍是严重威胁广州市工业系统不同行业职工生命的疾病。在预防工作中,不能忽视老年期的定期普查。
Background & Objective:Guangzhou is one of the advanced industry cities in China. To investigate the mortality of malignant tumor in workers from different industries can identify the high risk people who suffer from malignant tumor and have important significance to identify the relation between ocupational factors and malignant tumor. This study was designed to follow up the dead situation of malignant tumor in workers from different industries in Guangzhou,and provide the data for prevention and treatment of tumors. Methods: A total of 79573 workers, who exceed 35 years old, from 399 factories of Guangzhou were included in the prospective study for 8 years. It based on individual health files of 399 factories from 1989 to 1992. The total mortality, mortality of malignant tumor, and the disease classification of malignant tumor were investigated by epidemiology and statistics. Results: A total of 633869 people year (393373 men, 30195 women) have been trailed. The trailed time was more than 8 years. Of 1577 dead employees, 801 died of malignant tumor (50.7%). Of all the occupational types of work, the mortality of malignant tumor in metallurgical industry is apparently higher than that in other industries. In rubber industry, the relative risk of malignant tumor mortality in old age group is higher than that in middle age group. The top three malignant tumors of death were digestive system, respiratory system and rhinopharynx malignant tumors. While the top three mortalities for single organ malignant tumor were lung cancer, liver cancer, and rhinopharynx cancer. Conclusions: At present, malignant tumor is a disease which severely imperil the life of workers in different industries of Guangzhou. It is important to do health check periodically in old age group.
出处
《癌症》
SCIE
CAS
CSCD
北大核心
2002年第11期1254-1258,共5页
Chinese Journal of Cancer
