摘要
目的探讨并分析生长抑素联合普萘洛尔治疗肝硬化上消化道出血的临床疗效。方法选取在2017年1月~2017年12月期间收治的肝硬化上消化道出血患者共86例。随机将86例患者分为两组,对照组与试验组各43例患者,对照组患者采用生长抑素进行治疗,试验组患者在采用生长抑素治疗基础上加以普萘洛尔进行治疗。结果试验组患者临床疗效(88.37%)明显高于对照组患者(65.12%),试验组患者不良反应发生率(4.65%)明显低于对照组患者(20.93%),组间差异具有统计学意义(P<0.05)。结论采用生长抑素联合普萘洛尔治疗肝硬化合并上消化道出血患者,临床效果显著,可有效提高患者的临床疗效,同时降低患者的不良反应发生率,极大的降低了患者的出血量,提高了患者的生存质量与治疗质量。
Objective To investigate and analyze the clinical efficacy of somatostatin combined with propranolol in the treatment of upper gastrointestinal hemorrhage due to cirrhosis.Methods A total of 86 cirrhotic patients with upper gastrointestinal bleeding admitted to our hospital from January 2017 to December 2017 were enrolled.86 patients were randomly divided into two groups.The control group and the experimental group had 43 patients in each group.The control group was treated with somatostatin.The experimental group was treated with somatostatin and propranolol.Results The clinical efficacy of the experimental group(88.37%)was significantly higher than that of the control group(65.12%).The incidence of adverse reactions in the experimental group(4.65%)was significantly lower than that in the control group(20.93%).Conclusion The combination of somatostatin and propranolol has a clinical effect,which can effectively improve the clinical efficacy of patients,reduce the incidence of adverse reactions,greatly reduce the amount of bleeding and improve the quality of life and treatment of patients.
作者
程征宇
邓学杰
王琴
刘慧娟
CHENG Zhengyu;DENG Xue-jie;WANG Qin(Department of Gastroenterology,Leshan People's Hospital,Leshan,Sichuan 614000,China.)
出处
《中国处方药》
2019年第11期89-90,共2页
Journal of China Prescription Drug
关键词
生长抑素
普萘洛尔
肝硬化上消化道出血
Somatostatin
Propranolol
Cirrhotic patients with upper gastrointestinal bleeding
