摘要
目的分析尤瑞克林治疗分水岭脑梗死的临床疗效。方法将78例分水岭脑梗死患者随机分为观察组(39例)和对照组(39例),均给予抗血小板聚集、调脂、清除氧自由基、控制血压、控制血糖等脑梗死常规治疗。观察组在常规治疗基础上,加用尤瑞克林0.15肽核酸单位(PNA)静脉滴注,每天1次。两组疗程均为14d。比较两组患者治疗前后美国国立卫生院卒中量表(NIHSS)评分和缺血半暗带体积。比较两组治疗总有效率。结果治疗后,观察组NIHSS评分、缺血半暗带体积较治疗前明显下降(P<0.05),且NIHSS评分及缺血半暗带体积均明显低于对照组(P<0.05)。观察组治疗总有效率为84.62%,明显高于对照组(61.54%,P<0.05)。结论对于分水岭脑梗死,在脑梗死常规治疗基础上加用尤瑞克林,能够进一步改善神经功能,促进神经功能恢复。
Objective To observe the clinical effect of Ureklin on watershed cerebral infarction. Methods A total of 78 cases of watershed cerebral infarction were randomly divided into observation group(39 cases) and control group(39 cases),both of which were given cerebral infarction routine therapy.On the basis of routine therapy,the observation group was given combined therapy of Ureklin 0.15 PNA,static droplet for 1 time in every day.Both groups were treated for 14 d.Before and after treatment,the United States National Institutes of Health Stroke Scale(NIHSS) score and ischemic penumbra volume(IPV) were compared.The total effect rates of treatment were also compared. Results After treatment,the NIHSS score and IPV of observation group were significantly decreased,and were also lower than control group( P <0.05).The total effect rate of treatment in the observation group was 84.62%,which was higher than the 61.54% in the control group( P <0.05). Conclusion On the basis of conventional treatment of cerebral infarction,the addition of Ureklin could further improve the neurological function and promote the recovery of nervous function.
作者
林敬源
LIN Jingyuan(Department of Neurology,Fujian Province Geriatric Hospital,Fuzhou,Fujian 350000,China)
出处
《现代医药卫生》
2019年第20期3125-3127,3132,共4页
Journal of Modern Medicine & Health
