摘要
目的对前置胎盘产后出血预防中卡前列素氨丁三醇联合米索前列醇的效果进行探讨。方法方便选择收治前置胎盘孕妇140例,所有孕妇均于2018年1-12月在该院接受治疗,按照随机数字表法分为实验组(n=70)和常规组(n=70)。常规组应用缩宫素联合米索前列醇治疗,实验组应用卡前列素氨丁三醇联合米索前列醇治疗,观察两组疗效。结果实验组产后出血发生率14.29%,显著低于常规组的74.29%,差异有统计学意义(χ2=51.07,P<0.05)。实验组产后2 h出血量(270.64±50.45)mL、产后24 h出血量(382.95±75.14)mL,均显著低于常规组的(434.25±83.67)mL、(502.76±82.32)mL,差异有统计学意义(t=14.01、8.99,P<0.05)。实验组70例患者中6例腹泻、9例面色潮红、13例恶性,不良反应发生率40.00%;常规组70例患者中6例腹泻、8例面色潮红、12例恶心,不良反应发生率37.14%。两组不良反应发生率对比差异无统计学意义(χ2=0.12,P>0.05)。结论在前置胎盘产后出血预防中应用卡前列素氨丁三醇联合米索前列醇效果显著,并且安全性较高,值得进行广泛推广。
Objective To investigate the effect of carprostol tromethamine combined with misoprostol in the prevention of postpartum hemorrhage in placenta previa. Methods A total of 140 pregnant women with placenta previa were conveniently selected. All pregnant women were treated in this hospital from January to December 2018. They were divided into experimental group (n=70) and routine group according to random number table (n=70). The conventional group was treated with oxytocin combined with misoprostol. The experimental group was treated with carprostol tromethamine combined with misoprostol. The effects of the two groups were observed. Results The incidence of postpartum hemorrhage in the experimental group was 14.29%, which was significantly lower than that in the conventional group 74.29%,the difference was statistically significant(χ2=51.07, P<0.05). The amount of bleeding (270.64±50.45)mL in the experimental group and the bleeding volume (382.95±75.14)mL at 24 hours postpartum were significantly lower than those in the conventional group (434.25±83.67)mL and (502.76±82.32)mL,the difference was statistically significant(t=14.01, 8.99, P<0.05). Of the 70 patients in the experimental group, 6 case had diarrhea, 9 case had flushed color, 13 case had malignant, and the incidence of adverse reactions was 40.00%. Among the 70 patients in the conventional group, 6 case had diarrhea, 8 case had flushed color, 12 case had nausea, and the incidence of adverse reactions was 37.14%. There was no statistically significant difference in the incidence of adverse reactions between the two groups(χ2=0.12, P>0.05). Conclusion The application of carprostol tromethamine combined with misoprostol in the prevention of postpartum hemorrhage in placenta is significant and safe, and it is worthy of widespread promotion.
作者
周苏媛
ZHOU Su-yuan(Department of Obstetrics and Gynecology,Zaozhuang People's Hospital,Zaozhuang,Shandong Province,277100 China)
出处
《中外医疗》
2019年第25期115-117,共3页
China & Foreign Medical Treatment
