摘要
淫羊藿苷是一种从中草药淫羊藿的茎叶中提取出的有效活性物质。淫羊藿苷是一种粉状固体,其极易溶于醇类和脂类,不溶于水。近几年的研究发现,淫羊藿苷具有促进成骨、抑制破骨的作用,在临床上有一定的疗效。该文进一步探讨淫羊藿苷作用的分子机制,可以为应用成骨类药物促进患者正畸保持阶段牙齿稳定性、缩短保持时间提供理论依据。
Icariin is an effective active substance extracted from the stems and leaves of Chinese herbal medicine Epimedium. Icariin is a powdery solid that is highly soluble in alcohols and lipids and insoluble in water. In recent years, studies have found that icariin has the effect of promoting osteogenesis and inhibiting osteolysis, and has a certain clinical effect. This paper further exploration of the molecular mechanism of icariin can provide a theoretical basis for the application of osteogenic drugs to promote the stability of teeth during orthodontic maintenance and shorten the retention time.
作者
李雪
朱勇
王丹杨
张耀超
LI Xue;ZHU Yong;WANG Dan-yang;ZHANG Yao-chao(School of Stomatology,Xi'an Medical College,Xi'an,Shanxi Province,710021 China)
出处
《世界复合医学》
2019年第8期196-198,共3页
World Journal of Complex Medicine
基金
陕西省教育厅科学研究计划项目，淫羊藿苷促进正畸治疗后牙齿稳定性的实验研究（17JK0665）
关键词
淫羊藿苷
促进成骨
抑制破骨
Icariin
Promote osteogenesis
Inhibit bone breakage
