摘要
目的分析针灸联合药物疗法对脑梗死康复期患者疗效的影响。方法选取连云港市赣榆区人民医院2015年5月—2018年8月60例脑梗死康复期患者,根据不同治疗方法分组,观察组给予针灸联合药物疗法,对照组单纯药物治疗,对比两组疗效。结果观察组治疗后血清中神经营养因子(IGF-1、BDNF、NGF)含量分别为(115.64±13.97)μg/L、(4.86±1.57)ng/mL、(146.56±16.78)pg/mL,均明显高于对照组(t=56.632、10.241、28.927,P<0.05);观察组患者治疗后神经损伤因子(NSE、GFAP、S-100β、UCH-L1)含量低于对照组(t=10.824、18.937、8.236、5.931,P<0.05);观察组治疗后氧化应激指标均优于对照组(P<0.05)。结论针灸联合药物疗法能够改善患者神经功能,减轻神经功能损伤程度,避免全身氧化应激反应。
Objective To analyze the effect of acupuncture combined with drug therapy on the efficacy of patients with cerebral infarction during rehabilitation. Methods Sixty patients with cerebral infarction in the Lianyungang District People's Hospital from May 2015 to August 2018 were selected according to different treatment methods. The observation group was given acupuncture combined with drug therapy, and the control group was treated with drug alone. Efficacy of the two groups were compared. Results The levels of serum neurotrophic factors (IGF-1, BDNF, NGF) in the observation group were (115.64±13.97)μg/L,(4.86±1.57)ng/mL, and (146.56±16.78)pg/mL, respectively, which were significantly higher than the control group (t=56.632, 10.241, 28.927, P<0.05);the levels of nerve injury factors (NSE, GFAP, S-100β, UCH-L1) in the observation group were lower than those in the control group (t=10.824, 18.937, 8.236, 5.931, P<0.05);the oxidative stress index of the observation group was better than that of the control group (P<0.05). Conclusion Acupuncture combined with drug therapy can improve neurological function, reduce the degree of neurological damage and avoid systemic oxidative stress.
作者
谭伟
熊洁
TAN Wei;XIONG Jie(Lianyungang District People's Hospital,Lianyungang,Jiangsu Province,222100 China)
出处
《世界复合医学》
2019年第8期149-151,共3页
World Journal of Complex Medicine
关键词
针灸
脑梗死康复期
神经细胞因子
氧化应激
Acupuncture
Cerebral infarction rehabilitation period
Nerve cell factor
Oxidative stress
