摘要
代谢综合征(MetS)包含胰岛素抵抗,中心性肥胖,血脂异常和高血压。越来越多的证据表明,MetS成为良性前列腺增生(BPH)发展及相关的下尿路症状(LUTS)的男性重要危险因素之一。本文从MetS的定义及其在BPH-LUTS中的流行病学和生物学角度分析MetS与BPH-LUTS的关系,以及α-受体阻滞剂和5α-还原酶抑制剂、双胍类药物、他汀类药物及改变生活方式和减轻体重方式治疗BPH-LUTS合并MetS作一综述,以期为临床治疗提供参考。
Metabolic syndrome(MetS)contains insulin resistance,central obesity,dyslipidemia,and hypertension.There is increasing evidence that MetS is one of the major risk factors for men with benign prostatic hyperplasia(BPH)development and associated lower urinary tract symptoms(LUTS).This article analyzes the relationship between MetS and BPHLUTS from the definition of MetS and its epidemiology and biology in BPH-LUTS,as well asα-blockers and 5α-reductase inhibitors,biguanides,statins.A review of BPH-LUTS combined with MetS in the treatment of drugs and lifestyle changes and weight loss methods,in order to provide a reference for clinical treatment.
作者
刘柏基
熊波波
LIU Bai-ji;XIONG Bo-bo(Department of Urology,Yunnan Boya Hospital/the Second Affiliated Hospital of Kunming MedicalUniversity,Kunming 650000,Yunnan,China)
出处
《医学信息》
2019年第17期28-31,共4页
Journal of Medical Information
基金
国家自然科学基金(编号:81660422)
关键词
胰岛素抵抗
下尿路症状
代谢综合征
前列腺增生
Insulin resistance
Lower urinary tract symptoms
Metabolic syndrome
Benign prostatic hyperplasia
