摘要
生物可降解血管支架凭借其良好的生物相容性和完全可降解性,被认为能从根本上解决血管局部再狭窄问题,得到了广泛关注和研究。但现有的血管支架制造技术存在成型质量低,制造柔性差或成本高等问题。近年来,3D打印技术凭借其"增材制造"的独特优势,在生物医疗器械个性化制造方面优势明显。综合考虑支架的管网状结构特点,基于熔融沉积原理构建了一种四轴联动3D打印装置,即在笛卡尔型打印机主体上增加一个具有温控功能的旋转方向可控A轴装置,详细阐述了其结构组成和系统控制方案,并通过成型实验制备了两种新型聚合物支架结构,验证了四轴联动3D打印技术在可降解血管支架制备方面的可行性。
It has been recognized thatbiodegradable stents could effectively solve restenosis due to their biocompatibility and unique biodegradability. Therefore, biodegradable stents have received intensive attention and study, but some fabrication problems of the stents, like low quality, lack of flexibility or high price, are still unsettled. By virtue of its unique advantages of additive manufacturing, 3D printing technology has displayed great advantages in the manufacture of personalized biomedical devices in the past years. Considering the special structures of biodegradable stents, a novel four-axis 3D printer based on the principles of Fused Deposition Modeling is put forward where a controllable rotatable axis unit with temperature control is added on the Cartesian printer. Framework design and the corresponding control method are elaborated and feasibility and effectiveness of four-axis 3D printing technique for fabrication of biodegradable stents are proved through fabricating two kinds of new polymer stents.
作者
孙建兴
郭纯方
赵丹阳
SUN Jian-xing;GUO Chun-fang;ZHAO Dan-yang(School of Mechanical Engineering Dalian University of Technology, Liaoning Dalian 116024, China)
出处
《机械设计与制造》
北大核心
2019年第8期23-25,29,共4页
Machinery Design & Manufacture
关键词
3D打印
熔融沉积
四轴联动
生物可降解
血管支架
3D Printing
Fused Deposition Modeling(FDM)
Four-Axis Linkage
Biodegradable
Stents
