摘要
目的:分析医院碳青霉烯类抗菌药物临床不合理使用的原因,为临床合理用药提供参考。方法:抽取医院2018年1—12月期间采用碳青霉烯类抗菌药物治疗的住院患者623例资料,分析其病原学微生物送检率、药物选用的适应证、用法用量、联合用药等方面判断其用药的合理性。结果:623例临床使用碳青霉烯类抗菌药物治疗患者中,病原微生物送检率为95.83%,不合理用药135例,其不合理率为21.67%;其中位居前3位用药不合理的原因有药物选用不适宜、未送检病原微生物培养和联合用药不适宜为91例,占全部不合理用药的67.41%。结论:医院临床碳青霉烯类抗菌药物的使用尚需进一步加强干预管理,以提升合理使用水平。
Objective: To analyze the causes of unreasonable medication of carbapenems in clinic, and to provide a reference for clinical rational drug use. Methods: Data of 623 inpatients treated with carbapenems in hospitals from January to December 2018 were extracted, and the rationality of their use of pathogenic microorganisms was judged from the aspects of the detection rate, indications of drug selection, usage and dosage and combination of drugs. Results: Among the 623 cases of clinical use of carbapenems in clinic, the rates of pathogenic microorganisms were 95.83% and 135 cases of unreasonable medication were 21.67%.Among them, the TOP 3 reasons of unreasonable drug use were improper drug selection, improper cultivation of pathogenic microorganisms not sent for testing and improper combined drug use in 91 cases, accounting for 67.41% of all unreasonable drug use. Conclusion: Clinical medication of carbapenems in hospitals needs to be further strengthened in intervention management to improve the level of rational use.
作者
杨忠慧
钱妙嫤
YANG Zhong-hui;QIAN Miao-jin(Taicang Hospital Affiliated to Suzhou University, Taicang Jiangsu 215400, China;Taicang No.l People's Hospital, Taicang Jiangsu 215400, China)
出处
《抗感染药学》
2019年第6期951-954,共4页
Anti-infection Pharmacy
关键词
碳青霉烯类
抗菌药物
合理用药
不合理用药原因
carbapenems
antibacterials
rational use of drugs
causes of unreasonable medication
