摘要
慢性心力衰竭是不同病因引起器质性心血管病的临床综合征,是多种心脏疾患的终末阶段,也是临床常见的危重症,具有较高的死亡率。目前因为医疗水平的逐步提高和老龄化社会的到来,慢性心力衰竭发病率呈逐渐上升趋势。而近年来,中医药在基础及临床研究方面发展迅速,可从多途径、多环节、多靶点、多机制有效延缓心力衰竭的进程,改善症状和预后,降低再住院率和病死率,提高患者生活质量,中医药治疗慢性心力衰竭的优势日渐被人们关注。本文总结了近几年中医药治疗心力衰竭的相关作用机制,发现中医药治疗心力衰竭主要从以下几个作用途径:调节神经内分泌系统、抗心肌纤维化、抗心肌细胞凋亡、改善机体血流动力学、优化心肌能量代谢、调节体液因子等。
Chronic heart failure is a clinical syndrome of organic cardiovascular disease caused by different causes.It is the end stage of many heart diseases,and is also a common critical disease with high mortality.At present,due to the gradual improvement of medical level and the arrival of an aging society,the incidence of chronic heart failure is on the rise.In recent years, with the rapid development of traditional Chinese medicine(TCM)in basic and clinical research, TCM can prevent and treat heart failure from multiple ways, links, targets and mechanisms.It can effectively control the symptoms of patients with heart failure,improve prognosis,reduce the re-hospitalization rate and mortality rate, and improve the quality of life of patients.The advantages of TCM in treating chronic heart failure are increasingly concerned by people.This paper summarizes the mechanism of TCM in treating heart failure in recent years.It is found that TCM mainly plays a role in the treatment of heart failure in the following waysregulating neuroendocrine system,anti-myocardial fibrosis,anti-myocardial cell apoptosis,improving body hemodynamics,optimizing myocardial energy metabolism, regulating humoral factors and so on.
作者
刘彩霞
LIU Cai-xia(Internal Medicine No.1 Ward, Tianjin Nankai District Hospital of Traditional Chinese Medicine,Tianjin 300109, China)
出处
《中国城乡企业卫生》
2019年第7期99-101,共3页
Chinese Journal of Urban and Rural Enterprise Hygiene
关键词
心力衰竭
中医药
综述
Heart failure
Traditional Chinese medicine
Review
