摘要
目的了解北京地区18岁以上人群膝关节退行性骨关节炎流行病学特点,以及骨质疏松症与膝关节骨关节炎的相关性。方法采用横断面研究设计,并采用分层抽样的方法,抽取北京地区18岁以上常住人口,自行制定问卷(患病状况和可能影响因素)对研究对象进行面对面的问卷收集。膝关节退行性骨关节炎和骨质疏松症均为已在医院明确诊断的患者。首先对可能影响膝关节骨关节炎的因素进行单因素分析,然后多因素分析:控制性别、年龄、身体质量指数、腰臀比、教育水平、工作性质、工作强度、体育锻炼等因素的作用,采用Logistic多因素回归模型分析骨质疏松症对膝骨关节炎的独立作用。结果本组783例研究对象中,膝关节退行性骨关节炎53例,患病率为6.77%,患病率95%CI为(5.01%,8.53%)。<45岁组、45~59岁组和≥60岁组的患病率依次为2.54%、7.02%和16.67%,差异有统计学意义(χ^2=36.284,P=0.000)。在控制其他因素作用后,骨质疏松症对膝关节骨关节炎存在独立的影响(OR=3.56,95%CI:1.76,7.18)。结论年龄越大,退行性膝关节炎患病率越高;骨质疏松症与退行性膝关节炎存在相关性。
Objective To investigate the prevalence of degenerative knee osteoarthritis and the relationship between osteoporosis and knee osteoarthritis.Methods A community-based cross-sectional study was conducted and stratified sampling method was used to select the sample.The permanent residents over 18 years old in Beijing were selected,and self-developed questionnaires were used by face-to-face interview including the disease condition and possible relative factors.The effect of osteoporosis on knee osteoarthritis was analyzed after controlling the effect of gender,age,BMI,waist-hip ratio,education level,nature of work,intensity of work,physical exercise by the Logistic regression model.Results Among the 783 subjects,53 cases of knee degenerative osteoarthritis were found,with the prevalence rate was 6.77%and the prevalence rate of 95%CI was 5.01%,8.53%.The prevalence rates of<45 years old group,45-59 year-old group and≥60-year-old group were 2.54%,7.02%and 16.67%respectively,and the difference was statistically significant(χ^2=36.284,P=0.000).After controlling the other factors,osteoporosis had an independent effect on knee osteoarthritis with OR value of 3.56(95%CI:1.76,7.18).Conclusion The older the age,the higher the prevalence of degenerative knee arthritis,and there is a correlation between osteoporosis and degenerative knee arthritis.
作者
赵志宏
王锐
国宇
王恺
蒋毅
周敬滨
Zhao Zhihong;Wang Rui;Guo Yu;Wang Kai;Jiang Yi;Zhou Jingbin(Department of Orthopedics,Beijing Second Hospital,Beijing 100031,China;Department of sports Biomechanics,College of sports human science,Beijing sport university,Beijing 100084,China;Department of joint reconstructive surgery,Beijing Jishuitan Hospital,Beijing 100031,China;National Institute of Sports Medicine,Beijing 100061,China)
出处
《中华骨科杂志》
CAS
CSCD
北大核心
2019年第14期870-875,共6页
Chinese Journal of Orthopaedics
关键词
骨关节炎
膝
骨质疏松
患病率
横断面研究
Osteoarthritis,knee
Osteoporosis
Prevalence
Cross-sectional studies
