摘要
胎儿期是各器官系统迅速发展时期,对外界毒物较为敏感。胎儿期多环芳烃(PAHs)暴露将对胎儿发育以及出生后体格、神经心理行为的发育产生重要影响,但国内关于这方面的研究较为少见。笔者从多环芳烃的暴露途径、胎儿期多环芳烃暴露对妊娠结局的影响、胎儿期多环芳烃暴露对儿童生理的影响、胎儿期多环芳烃暴露对儿童神经心理行为发育的影响、多环芳烃影响胎儿发育的机制五个方面进行了综述,为后续开展此类研究以及相关保护性政策的制定提供依据。
The organ systems of embryo develop rapidly and are more sensitive to xenobiotics. Prenatal exposure to polycyclic aromatic hydrocarbons(PAHs) has significant impacts on fetal development as well as postnatal physical and neurobehavioral development,but there is still rare domestic research in this field. In order to provide the basis for the future research and protective policies,this paper reviewed literatures on PAHs based on five aspects,namely,the exposure pathways,effects on pregnancy outcome,effects of prenatal exposure to PAHs on children'sphysiology,effects of prenatal exposure to PAHs on children's neurobehavioral development and the mechanism of PAHs on fetal development.
作者
段小倩
程子茜
杜雨峰
窦妍
张敬旭
DUAN Xiao-qian;CHENG Zi-xi;DU Yu-feng;DOU Yan;ZHANG Jing-xu(School of Public Health, Peking University, Beijing 100191 ,China)
出处
《环境与健康杂志》
CAS
北大核心
2018年第12期1104-1108,共5页
Journal of Environment and Health
关键词
胎儿期
多环芳烃
妊娠结局
儿童早期发展
Fetal period
Polycyclic aromatic hydrocarbons (PAHs)
Pregnancy outcome
Early development
