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食管癌肿瘤标志物研究及临床应用进展 被引量:17

Advances in research and clinical application of tumor markers in esophageal cancer
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摘要 食管癌是常见的上消化道恶性肿瘤。该疾病早期症状不明显,发现时往往是晚期,导致其较高的发病率和病死率。男性、女性的食管癌发病率、死亡率均位列所有常见癌肿的前10位。早期发现、早期治疗是降低食管癌发病率、病死率的有效手段,肿瘤标志物在食管癌早期诊断、治疗监测、预后评估等临床应用环节发挥重要作用。文章阐述了临床现有食管癌相关肿瘤标志物的应用及食管癌新标志物的探索和应用进展。 Esophageal cancer is a common malignant tumor of the upper gastrointestinal tract. Early symptoms of the disease are inconspicuous and the disease is often diagnosed at a later stage, leading to higher morbidity and mortality. Esophageal cancer morbidity and mortality in both genders ranks among the top 10 most common cancers. Early detection and early treatment are effective means to reduce the incidence and mortality of esophageal cancer. Tumor markers play an important role in early diagnosis, treatment monitoring and prognosis evaluation of esophageal cancer. This paper reviews the clinical application of tumor markers related to esophageal cancer and the exploration and application progress of new tumor markers for esophageal cancer.
作者 孟茜茜 张子凡 程志远 王天骄 林寒 辛磊 张玲 王洛伟 李兆申 MENG Qian-qian;ZHANG Zi-fan;CHENG Zhi-yuan;WANG Tian-jiao;LIN Han;XIN Lei;ZHANG Ling;WANG Luo-wei;LI Zhao-shen(Department of Gastroenterology,Changhai Hospital,Naval Medical University,Shanghai 200433,China)
出处 《中国实用内科杂志》 CAS CSCD 北大核心 2019年第7期634-639,共6页 Chinese Journal of Practical Internal Medicine
关键词 肿瘤标志物 食管癌 诊断 食管鳞癌 tumor markers esophageal cancer diagnosis ESCC
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