摘要
目的了解本地区慢性荨麻疹患者的吸入性和食入性过敏原情况,为临床预防和治疗提供依据。方法采用AutoBlot System 敏筛过敏原检测系统进行过敏原 SIgE 检测,采用西门子公司的化学发光仪系统进行总 IgE 检测。结果 394例慢性荨麻疹患者中总 IgE 阳性率为 68. 0%,sIgE 阳性率为 58. 6%,吸入性过敏原检测阳性率明显高于食入性过敏原检测阳性率;吸入性过敏原检测阳性率前 3 位是户尘螨/粉尘螨、猫/狗毛皮屑、矮豚草/蒿;食入性过敏原检测阳性率前 3 位是鸡蛋白、牛奶、鱼/虾/蟹;成人组 SIgE 过敏原阳性率明显高于儿童组。结论慢性荨麻疹患者以吸入性过敏原为主,吸入性过敏原是诱发慢性荨麻疹的重要因素,慢性荨麻疹患者进行过敏原检测,找出致病原因,对慢性荨麻疹的预防、治疗具有重要的临床意义。
Objective To gain an understanding about the conditions of local chronic urticaria patients’allergens through inhalation and ingestion,so as to provide theoretical basis for clinical prevention and treatment. Methods Allergen SIgE was detected by using the AutoBlot System,and Total IgE was detected by Chemoluminesence System. Results Out of 394 chronic urticaria samples,the total positive rate of IgE was 68. 0%,and that of sIgE was 58. 6%;The positive rate of inhalation aller-gens were apparently higher than that of ingestion allergens. The top three inhalation allergens included dustmites,cat /dog dander and hair,and short ragweed /artemisia;and the top three in the ingestion group included chicken protein,milk,and fish /shrimp /crab. The SIgE positive rate of adults group was evidently higher than that of minors. Conclusion Inhalation allergens play a major role in causing chronic urticaria,and thus allergen tests for urticaria patients are clinically instrumental in identifying the source,preventing and treating the disease.
作者
方莉萍
邵丽佳
孙冬梅
胡俊青
FANG Li-ping;SHAO Li-jia;SUN Dong-mei;HU Jun-qing(Jinhua Municipal Central Hospital,Jinhua,Zhejiang 321000,China)
出处
《中国卫生检验杂志》
CAS
2019年第12期1497-1498,共2页
Chinese Journal of Health Laboratory Technology
