摘要
目的探究高压氧治疗脑梗死并阻塞性睡眠呼吸暂停低通气综合征(OSAHS)的临床疗效,并分析对患者心理情绪变化及生活能力的影响。方法选取124例脑梗死并OSAHS患者为观察对象,随机分为对照组与高压氧组,每组62例。对照组给予患者相关常规治疗,包括药物治疗、改善循环及脑供血等;高压氧组在对照组基础上给予患者高压氧治疗。观察2组患者治疗前后抑郁、焦虑、卒中以及生活能力评分,同时比较2组患者治疗后临床治疗总有效率,分析不良反应情况。结果治疗前2组患者脑卒中评分、焦虑、抑郁以及生活能力评分比较差异无统计学意义(P>0.05);治疗后,高压氧组患者卒中评分、焦虑、抑郁及生活能力评分改善均明显优于对照组(P均<0.05);高压氧组患者治疗总有效率与对照组比较(95.16%vs 80.65%),差异有统计学意义(P<0.05);2组治疗过程中均出现不同程度的胃胀气、皮肤损伤、口舌干燥等不良反应,但经对症治疗后均有显著改善,且2组患者不良反应发生率比较差异无统计学意义(P>0.05)。结论高压氧治疗脑梗死并OSAHS能够获得确切疗效,改善患者的生活能力,缓解患者焦虑与抑郁情绪,临床应用方面具有较高的参考价值。
Objective To investigate the therapeutic effects of hyperbaric oxygen on cerebral infarction complicated by obstructive sleep apnea hypopnea syndrome(OSAHS),and to explore its effects on psychological mood and life ability of patients with cerebral infarction complicated by OSAHS.Methods A total of 124 patients with cerebral infarction complicated by OSAHS were randomly divided into control group(n=62) and hyperbaric oxygen group(n=62).The patients in control group were treated by routine therapy,including drug therapy,improved circulation and cerebral blood supply,however,the patients in hyperbaric oxygen group were treated by hyperbaric oxygen on the basis of control group.The depression,anxiety and life ability scores were observed before and after treatment in both groups.Moreoverr the total effective rate and incidence rate of adverse reactions were observed and compared between the two grousp.Results Before treatment there were no significant differences in the scores of stroke,anxiety,depression and ability of life between the two groups(P>0.05).After treatment the improvement degree of depression and living ability scores in hyperbaric oxygen group was more significant than that in control group(P<0.05),and the total effective rate in hyperbaric oxygen group was 95.16%,which was significantly higher than that(80.65%) in control group(P<0.05).There was no significant difference in the incidence rate of adverse reactions between the two groups(P>0.05).Conclusion The hyperbaric oxygen in treatment of cerebral infarction complicated by obstructive sleep apnea hypopnea syndrome can obtain definite curative effects,which can improve the living ability of patients,relieve anxiety and depression emotion of patients,it is of significance in clinical practice.
作者
王治霞
徐俊芳
孙珊珊
WANG Zhixia;XU Junfang;SUN Shanshan(Department of Hyperbaric Oxygen,Shiyan People’s Hospital Affiliated to Hubei Medical College,Hubei,Shiyan 442000,China)
出处
《河北医药》
CAS
2019年第11期1703-1705,1709,共4页
Hebei Medical Journal
关键词
脑梗死
高压氧
阻塞性睡眠呼吸暂停低通气综合征
生活能力
cerebral infarction
hyperbaric oxygen
obstructive sleep apnea hypopnea syndrome
life ability
