摘要
目的探究氯吡格雷联合低分子肝素钙治疗进展性缺血性脑卒中临床效果分析。方法该院在2017年3月—2019年2月期间共接诊治疗过16例进展性缺血性脑卒中患者,经患者及患者家属同意后,对患者给予氯吡格雷联合低分子肝素钙进行治疗,治疗期间,给予患者低分子肝素钙5000IU进行皮下注射,每日注射2次,患者同时口服氯吡格雷,一次(75mg)一片或一次三片(25mg),1次/d,治疗时长为5~10d。治疗期间,医护人员对患者的病情恢复情况和生活质量改善情况进行详细记录并分析,如有紧急情况,立即通报主治医师并协助治疗。结果16例进展性缺血性脑卒中患者治疗后DNS评分(3.9±0.56)分明显低于患者治疗前DNS评分(10.4±1.62)分,差异有统计学意义(P<0.05)。结论氯吡格雷联合低分子肝素钙可以大幅度提升进展性缺血性脑卒中患者的病情恢复速度,并且安全可靠,无副作用,值得被广泛的推广使用。
Objective To explore the clinical effect of clopidogrel combined with low molecular weight heparin calcium in the treatment of progressive ischemic stroke.Methods From March 2017 to February 2019,16 patients with progressive ischemic stroke were treated in our hospital.With the consent of the patients and their families,the patients were treated with clopidogrel combined with low molecular weight heparin calcium.During the treatment period,the patients were injected with low molecular weight heparin sodium 5 000 IU subcutaneously twice a day.At the same time,the patient took clopidogrel orally,one tablet (75 mg) or three tablets (25 mg) once a day for 5~10 days.During the treatment period,the medical staff recorded and analyzed the patient's recovery and quality of life improvement in detail.In case of emergency,they immediately notified the attending physician and assisted the treatment.Results The postoperative DNS score (3.9±0.56)points in 16 patients with progressive ischemic stroke was significantly lower than the pre-treatment DNS score (10.4±1.62)points.The difference were statistically significant (P<0.05).Conclusion Clopidogrel combined with low molecular weight heparin calcium can significantly improve the recovery rate of patients with progressive ischemic stroke,and it is safe,reliable and without side effects.It is worth being widely used.
作者
程世宏
CHENG Shi-hong(Department of Brain Medicine,Shangrao Municipal Hospital,Shangrao,Jiangxi Province,334000 China)
出处
《系统医学》
2019年第8期46-48,共3页
Systems Medicine
关键词
氯吡格雷
低分子肝素钙
缺血性脑卒中
Clopidogrel
Low molecular weight heparin calcium
Ischemic stroke
