摘要
目的:比较慢性肾衰竭尿毒症患者应用高通量和低通量血液透析的临床疗效。方法:选取60例慢性肾衰竭尿毒症患者为研究对象,将其分为对照组和观察组各30例。对照组给予低通量血液透析,观察组给予高通量血液透析,比较两组的疗效。结果:观察组总有效率高于对照组(P<0.05)。两组治疗前炎症反应指标组间比较差异无统计学意义(P>0.05),两组治疗后炎症反应指标均下降,且观察组治疗后炎症反应指标低于对照组(P<0.05)。结论:给予慢性肾衰竭尿毒症患者高通量血液透析治疗,既可提高疗效,也利于降低炎症反应指标。
Objective: To compare the efficacy of high and low-throughput hemodialysis in the treatment of chronic renal failure uremia. Methods: A total of 60 patients with chronic renal failure uremia were selected and randomly divided into a control group and an observation group with 30 cases each according to the method of dialysis. The patients were treated with low-throughput hemodialysis in the control group and high-throughput hemodialysis in the observation group. The effect was compared between the two groups. Results: The total effective rate of treatment was significantly lower in the control group than the observation group (P<0.05). The comparison of inflammatory response indexes such as the levels of C-reactive protein (CRP), interleukin-6 (IL-6) and tumor necrosis factor (TNF-a) showed no significant differences before treatment (P>0.05). The inflammatory response indexes in the two groups were all reduced and were lower in the observation group than the control group (P<0.05). Conclusion: High-throughput hemodialysis can not only improve the therapeutic effect of chronic renal failure uremia but also reduce the level of inflammation.
作者
郑涛
李敏
鄢琦玲
ZHENG Tao;LI Min;YAN Qiling(Blood Dialysis Room, Municipal Hospital of Shangrao City, Jiangxi Shangrao 334000, China)
出处
《上海医药》
CAS
2019年第11期41-43,共3页
Shanghai Medical & Pharmaceutical Journal
关键词
慢性肾衰竭尿毒症
高通量血液透析
低通量血液透析
chronic renal failure uremia
high-throughput hemodialysis
low-throughput hemodialysis
