摘要
目的:建立朱砂药材及饮片XRD Fourier指纹图谱,并比较朱砂水飞前后XRD Fourier指纹图谱的变化。方法:采用粉末X射线衍射(X-ray diffraction,XRD)技术测定其XRD Fourier指纹图谱,同时进行模糊聚类法分析和相似度评价。结果:建立了以11个共有峰为特征指纹信息的13批朱砂药材和17批朱砂饮片的XRD Fourier指纹图谱分析方法;朱砂药材及饮片的XRD Fourier指纹图谱的相似度分别为0.941～0.997、0.993～1.000。药材与饮片的XRD Fourier特征图谱峰无明显差异。结论:XRD Fourier指纹图谱分析法可用于朱砂药材及饮片的鉴定与分析。
Objective:To establish X-ray diffraction(XRD)Fourier fingerprint of Cinnabaris medicinal materials and decoction pieces,and to compare the changes of XRD Fourier fingerprints before and after water grinding.Methods:XRD Fourier fingerprints were determined by powder X-ray diffraction(XRD)technique,and analyzed by fuzzy clustering method and similarity evaluation.Results:XRD Fourier fingerprint analysis method was established for 13 batches of Cinnabaris medicinal materials and 17 batches of Cinnabaris decoction pieces with 11 common peaks as Characteristicis fingerprints.The similarity of XRD Fourier fingerprints of Cinnabaris medicinal materials and decoction pieces were 0.941~0.997 and 0.993~1.000,respectively.There were no significant differences in the XRD Fourier characteristic peaks between Cinnabaris medicinal materials and decoction pieces.Conclusion:XRD Fourier fingerprinting method can be used for identification and analysis of Cinnabaris medicinal materials and decoction pieces.
作者
杨丹
刘圣金
燕珂
马宏跃
李全
王恒斌
狄留庆
YANG Dan;LIU Sheng-jin;YAN Ke;MA Hong-yue;LI Quan;WANG Heng-bin;DI Liu-qing(College of Pharmacy ,Nanjing University of Chinese Medicine/Jicingsu Engineering Research (Meiller for Kffieient Delivery System of TCM ,Nanjing Engineering and Technology Research Center for TCM Pellets,Nanjing 210023,China;Suzhou Leiyunshang Phannaceulical Co. Ltd ,Suzhou 215009,China)
出处
《中药材》
CAS
北大核心
2018年第12期2767-2773,共7页
Journal of Chinese Medicinal Materials
基金
国家中药标准化项目(ZYBZH-C-JS-30)
江苏科技成果转化项目(BA2016104)
江苏高校“青蓝工程”项目
江苏高校优势学科建设工程资助项目(PAPD)
江苏省产学研合作项目(FZ20140109)
江苏省研究生实践创新计划项目(SJCX18-0451).
关键词
矿物药
朱砂
水飞
X射线衍射
指纹图谱
质量控制
Mineral Chinese medicine
Cinnabaris
Water grinding
X-ray diffraction
Fingerprint
Quality control
