摘要
EB病毒作为儿童常见的病毒病原,其感染可引发儿童肿瘤、免疫相关性疾病和呼吸系统相关性疾病。我国儿童EB病毒感染的比例高,原发感染年龄早。其发病主要与B淋巴细胞、自然杀伤细胞以及基因缺陷密切相关。临床EB病毒感染除与儿童肿瘤和免疫相关性疾病相关外,引起的呼吸系统相关性疾病更值得关注。
Epstein-Barr virus (EBV) is a common viral pathogen in children.EBV infection can cause childhood tumors, immune-related diseases and respiratory-related diseases.The proportion of EBV infection in Chinese children is high and the age of primary infection is early.Its pathogenesis is closely related to B lymphocytes, natural killer cells and gene defects.Clinical EBV infection is not only associated with childhood tumors and immune-related diseases, but also causes respiratory-related diseases that deserve more attention.
作者
张建华
孙静怡
陈梦雪
Zhang Jianhua;Sun Jingyi;Chen Mengxue(Department of Pediatrics,Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine,Shanghai 200092,China)
出处
《中华实用儿科临床杂志》
CSCD
北大核心
2019年第10期725-729,共5页
Chinese Journal of Applied Clinical Pediatrics
关键词
儿童
EB病毒感染
呼吸系统相关性疾病
Child
Epstein-Barr virus infection
Respiratory-related diseases
