摘要
慢性阻塞性肺疾病(COPD)在全球的发病率不断地上升,在我国发病率以及死亡率也居高不下,临床对于COPD的研究有很多,包括预防、诊断以及治疗等方面,很大程度上提高了人们对于COPD的认知。但是,目前对于COPD的发病机制尚无明确定论,公认的主要为炎症、蛋白酶-抗蛋白酶失衡以及氧化-抗氧化失衡这三种学说,但是近几年来,研究者在这三种发病机制有了更深的研究,也发现了新的可能的发病机制,本文将对此进行阐述,为COPD的诊治提供理论参考。
The incidence of chronic obstructive pulmonary disease (COPD) is increasing globally, and the incidence and mortality in China are also high. There are many clinical studies on COPD, including prevention, diagnosis and treatment. Increased awareness of COPD. However, there is no clear-cutting theory about the pathogenesis of COPD. It is generally recognized as the three theories of inflammation, protease-antiprotease imbalance and oxidative-antioxidative imbalance. However, in recent years, researchers have had these three pathogenesis mechanisms. Deeper research has also discovered new possible pathogenesis, which will be elaborated in this paper to provide a theoretical reference for the diagnosis and treatment of COPD.
作者
马宏境
刘彬
MA Hong-jing;LIU Bin(Department of Respiratory,Tianjin Fifth Central Hospital, Tianjin 300450,China;Department of Emergency Medicine2,Tianjin Fifth Central Hospital, Tianjin 300450,China)
出处
《医学信息》
2019年第10期50-52,共3页
Journal of Medical Information
关键词
慢性阻塞性肺疾病
COPD
呼吸系统
发病机制
Chronic obstructive pulmonary disease
COPD
Respiratory system
Pathogenesis
