摘要
支气管哮喘是一种气道慢性炎症性疾病,可引起不同程度可逆性气道阻塞症状,表现出反复发作性喘息、呼吸困难、胸闷或咳嗽等,给儿童身心健康及其家庭带来严重影响。近几年来,该病发病率及病死率呈现逐年上升趋势,但发病机制较复杂,目前尚未完全清楚。维生素D缺乏与多种疾病的发生发展存在密切联系,包括哮喘。近年来国内外学者已开始关注维生素D水平与哮喘的关系,希望为临床防治哮喘提供新的思路。该综述主要就维生素D水平与支气管哮喘关系的研究进展进行阐述,深入理解两者之间的联系,将为哮喘提供更有效的治疗靶点和思路。
Asthma is an airway chronic inflammatory disease involving inflammatory cells of the airways.Chronic inflammation of the airway in children with asthma can cause reversible airway obstruction with varying degrees of recurrent air wheezing, dyspnea, chest tightness or coughing, which can have serious effects on children′s physical and mental health and their families.In recent years, the incidence and mortality of the disease have been increasing year by year, but the pathogenesis is more complicated and not fully understood.Many studies have found that vitamin D deficiency had a certain relationship with the occurrence and development of asthma, which may provide new ideas for clinical prevention and treatment of asthma.Therefore, the relationship between vitamin D and asthma has become one of the hot topics of current researches.There are a lot of related research reports.This review mainly describes the current research progress on the relationship between vitamin D levels and bronchial asthma, and provides deep understanding of the relationship between the two, which may bring more effective therapeutic targets and ideas for asthma.
作者
王莹莹(综述)
程航
路程
成焕吉(审校)
Wang Yingying;Cheng Hang;Lu Cheng;Cheng Huanji(Department of Pediatrics, the First Hospital of Jilin University, Changchun 130021, China)
出处
《国际儿科学杂志》
2019年第4期268-271,共4页
International Journal of Pediatrics
基金
国家自然科学基金(81800021).
