摘要
目的研究阿奇霉素联合甲泼尼龙对重症支原体肺炎患儿临床效果和免疫功能的影响。方法选取2016年6月—2018年12月我院重症支原体肺炎患儿80例,随机分成对照组(采取阿奇霉素治疗)和观察组(采取阿奇霉素联合甲泼尼龙治疗),对比两组患儿临床症状消失时间、住院时间以及细胞免疫指标。结果观察组患儿的各项症状消失时间和住院时间短于对照组(P <0.05)。观察组患儿的CD4^+和CD4^+/CD8^+高于对照组,而CD8^+低于对照组(P <0.05)。结论阿奇霉素联合甲泼尼龙治疗重症支原体肺炎患儿效果显著,可有效加快患儿康复,改善患儿的免疫功能。
Objective To study the clinical effect and immune function of azithromycin combined with methylprednisolone in children with severe mycoplasma pneumonia.Methods 80 children with severe mycoplasma pneumonia in our hospital from June 2016 to December 2018 were randomly divided into control group (treated with azithromycin) and observation group (treated with azithromycin combined with methylprednisolone).The disappearance time of clinical symptoms,hospitalization time and cellular immune indexes of the two groups were compared.Results The disappearance time and hospitalization time of symptoms in the observation group were shorter than those in the control group (P < 0.05).The levels of CD4+,CD4+/CD8+ in the observation group were higher than those in the control group,while the levels of CD8+ in the observation group were lower than those in the control group (P < 0.05).Conclusion Azithromycin combined with methylprednisolone is effective in treating children with severe mycoplasma pneumonia,which can effectively accelerate the recovery of children and improve their immune function.
作者
蓝春富
LAN Chunfu(Department of Pediatrics,Chongzuo Maternal and ChildHealth Hospital,Chongzuo Guangxi 532200,China)
出处
《中国卫生标准管理》
2019年第7期71-73,共3页
China Health Standard Management
关键词
支原体肺炎
阿奇霉素
甲泼尼龙
临床症状
住院时间
免疫功能
mycoplasma pneumonia
azithromycin
methylprednisolone
clinical symptoms
hospitalization time
immune function
