摘要
妊娠期糖尿病属于代谢性疾病,表现为糖脂代谢、能量转换的异常,严重危害母儿健康。代谢组学与基因组学、转录组学、蛋白质组学并列,是新兴发展的研究技术,可反映机体系统全面的生理和病理状态。本文对国内外最新文献,从代谢组学研究方法、妊娠期糖尿病代谢组学研究概况及相关研究进行综述,并对该领域的研究进行展望。
As a metabolic disease, gestational diabetes mellitus (GDM) is characterized by abnormality in both glucolipid metabolism and energy conversion, which might severely impair the maternal and child health. Metabolomics, together with genomics, transcriptomics and proteomics, are emerging research technology focusing on the overall physiological and pathological states of the body system. This article summarized the advances of researches in metabolomics in GDM from the perspective of methodology to the research prospect in this field.
作者
晋柏
孙丽洲
Jin Bai;Sun Lizhou(Department of Obstetrics,the First A ffiliated Hospital of Nanjing Medical University,Jiangsu Women and Children Health Hospital,Nanjing 210029,China)
出处
《中华围产医学杂志》
CAS
CSCD
北大核心
2019年第4期265-268,共4页
Chinese Journal of Perinatal Medicine
关键词
糖尿病
妊娠
代谢组学
Diabetes, gestational
Metabolomics
